Anti-proliferation

Stachyose
Catalog No: CFN90424

Stachyose, as prebiotics, can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine.Stachyose inhibits Caco-2 cell proliferation and induces apoptosis in a dose-dependent manner. Stachyose with an RS3 carrier has better preventative effects on colitis than Stachyose alone in mice.

Mevastatin
Catalog No: CFN90426

Mevastatin inhibits HMGCR (HMG-CoA reductase) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin inhibits the differentiation of TAO derived orbital preadipocytes by blocking PPAR-gamma mRNA expression. Mevastatin induces cell growth inhibition and apoptosis in SACC cells, it triggers the phosphorylation of the EGFR and inhibits the c-Jun N-terminal kinase pathway.

Osthenone
Catalog No: CFN97853

Osthenone shows strong activity against the cancer cell lines, whereas it has weak antiproliferative activity against the normal human cell lines.

Eurycomanone
Catalog No: CFN92008

Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.

Desmethylxanthohumol
Catalog No: CFN92015

Desmethylxanthohumol shows estrogenic activity.