Anti-proliferation

10-Hydroxy-2-decenoic acid
Catalog No: CFN90512

10-Hydroxy-2-decenoic acid is a potential HDACI which inhibits the proliferation of FLS cells by PI3K-AKT pathway; it exerts an inhibitory effect on VEGF-induced angiogenesis, partly by inhibiting both cell proliferation and migration. 10-Hydroxy-2-decenoic acid activates AMPK, and insulin independently enhances glucose uptake following translocation of Glut4 to PM; it also can prevent UVA-induced damage and inhibit MMP-1 and MMP-3 expressions.

Rosamultic acid
Catalog No: CFN92608

Rosamultic acid is a class of triterpenes with α-glucosidase inhibitory activity.

Isocurcumenol
Catalog No: CFN92618

Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).

7-O-Prenylscopoletin
Catalog No: CFN92639

7-O-Prenylscopoletin and cedrelopsin show high antiproliferative activities against cancer cell lines.

(-)-beta-Peltatin-5-O-beta-D-glucopyranoside
Catalog No: CFN92700

beta-Peltatin-5-O-beta-D-glucopyranoside provides potent cancer cell growth inhibitory activity (GI50 0.1 to <0.03 ug/mL) against a panel of six human cancer cell lines and one murine cancer cell line; it also shows modest antiproliferative activities against the A2780 ovarian cancer cell line, with the IC50 value of 4.9 ± 0.1 uM.