Aloin
Catalog No: CFN96950
Aloe components (aloin, aloesin and aloe-gel) show anti-inflammatory effects, they can ameliorate intestinal inflammatory responses in a dextran sulfate sodium (DSS)-induced ulcerative colitis rat model. Aloin shows tyrosinase activity, it could be used as lightening agents in the treatment of hyperpigmentation disorders and cosmetic additives. Aloin is a potent proapoptotic agent, it showed a pronounced antiproliferative effect at physiological concentration (IC50 = 97 microM), caused cell cycle arrest in the S phase and markedly increased HeLaS3 cell apoptosis (to 24%).
Aloin A
Catalog No: CFN99943
Plants containing aloin A, aloe emodin, and structurally related anthraquinones have long been used as traditional medicines and in the formulation of retail products such as laxatives, dietary supplements, and cosmetics; however, topically applied aloe emodin increases the sensitivity of skin to UV light, although aloin A is not directly photocytotoxic, but human skin fibroblasts can metabolize aloin A to aloe emodin. Aloin A and aloe emodin have antibacterial activity against Gram-positive and Gram-negative bacteria.