Alphitolic acid
Catalog No: CFN99896
Alphitolic acid is a potent Hh/GLI signaling inhibitor, it shows an important relationship between Hh/GLI signaling inhibition, the decrease of BCL2, and cytotoxicity against cancer cells. Alphitolic acid has anti-inflammatory, antitumour, and antimicrobial activities, it can suppress the proliferation of SCC4 and SCC2095 OSCC cells with IC50 values of 12 and 15 uM, respectively, via apoptotic induction, this drug effect on apoptosis is, in part, associated with its ability to block Akt-NF-κB signalling; it could as an ingredient in functional food/dietary supplement for OSCC prevention.
Alpinumisoflavone
Catalog No: CFN98440
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is endowed with estrogenic properties accounting, at least in part, for E. lysistemon effects. Alpinumisoflavone induces cell death, may be via repressing both the ERK/MAPK and NF-κB pathways. Alpinumisoflavone is active against both Gram-negative and Gram-positive bacteria, the minimum inhibitory concentration values obtained (MIC) ranged from 3.9 ug/mL to 125 ug/mL.
