Hot Products

Ajmaline
Catalog No: CFN93513

Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations.

Ajugacumbin A
Catalog No: CFN92752

Reference standards.

Ajugasterone C
Catalog No: CFN90616

Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.

Ajugol
Catalog No: CFN90759

Ajugol shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).

Akuammigine
Catalog No: CFN97710

Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. Akuammidine also shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively.

Alantolactone
Catalog No: CFN99934

Alantolactone, an allergenic sesquiterpene lactone, has significant antitumor effects on malignant tumor cells, it can suppress inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells, and inhibit cell proliferation by interrupting the interaction between Cripto-1 and activin receptor type II A in activin signaling pathway.

Alatamine
Catalog No: CFN92121

Alatamine can markedly reduce acute myocardial ischemia (AMI)-induced cardiac injury and cardiac myocyte apoptosis, improve the expression and activity of sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase (SERCA).

Albanin A
Catalog No: CFN92325

Albanin A shows mushroom tyrosinase inhibitory activity, the IC50 value is 463 uM.

Albaspidin AA
Catalog No: CFN98474

Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM). It may have in vitro nematocidal activity against L4 stage larvae.

Albiflorin
Catalog No: CFN99774

Albiflorin has anti-inflammatory, and antidepressant-like effects. Albiflorin may reduce or prevent osteoblast degeneration in osteoporosis, and may promote the recovery of bone marrow hemopoietic function in a myelosuppressed mouse model, it has neuroprotective effect on primary hippocampal cells against β-amyloid induced toxicity.