Anemonine
Catalog No: CFN90524
Anemonin, a naturally occurring selective iNOS inhibitor, it has potential anti-inflammatory effect; it is also a potent protective molecule for osteoarthritis, it delays osteoarthritis progression by suppressing ECM loss and chondrocyte hypertrophy partially by suppressing IL-1β/NF-κB pathway activation. Anemonin can alleviate nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway.
Anemonin inhibits melanin synthesis by inhibiting the transcription of the genes encoding MITF, TYR, TRP1, and TRP2.
Anemoside B4
Catalog No: CFN99786
1. Anemoside B4(AB4) and tetrandrine(Tet) have some reversal effect on resistant to L-OHP in Lo Vo/L-OHP cells, the molecular mechanism of the resistance reverse effect was related to down-regulation of P-gp for AB4 and down-regulation of z DHHC9 for Tet.
2. Anemoside B4 can inhibit the production of IL-6,secretion of IL-8, downregulate E-selectin expression, and decrease the content of TXB(2), it reduces inflammatory response, thus relieving intestinal dysfunction via multiple pathways.
3. Anemoside B4 may potentially have a capacity to regulate immune responses in vivo via changes in production of these select cytokines by infected endothelial cells.
Anethole
Catalog No: CFN98550
Anethole has antispasmodic, anti-inflammatory, cardiovascular, and gastroprotective effects. Anethole can act as the CXCR4 antagonist and as the PTEN activator which resulted to PI3K/AKT-mediated inhibition of the metastatic prostate cancer progressions. Anethole may have a potent inhibitory effect on PD through suppression of pro-inflammatory molecules, it could be a novel therapeutic strategy for Periodontitis. Anethole blocks neuronal excitability,and induces the blockade of neuromuscular transmission. trans-Anethole has insecticidal activity to adult fruit flies of Ceratitis capitata, Bactrocera dorsalis, and Bactrocera cucurbitae.
