Hot Products

7Beta-Hydroxycholesterol
Catalog No: CFN90610

7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells. 7beta-Hydroxycholesterol and 7-ketocholesterol have dual cytotoxic effects on the cells of the vascular wall by their ability to induce apoptosis in endothelial and smooth muscle cells and necrosis in fibroblasts. 7beta-Hydroxycholesterol can inhibit the proliferation of NCI-H460 cells through apoptosis via caspase activation. It can reinforce the susceptibility of K562 adriamycin-resistant cells to this drug, it also can enhance radiosensitivity in RDM4 cells.

7-beta-Hydroxylathyrol
Catalog No: CFN92488

Reference standards.

7-Epi-10-deacetyltaxol
Catalog No: CFN89397

7-Epi-10-deacetyltaxol shows IC50 values of 0.085 nM, against HeLa cells.

7-Epitaxol
Catalog No: CFN90371

7-Epitaxol is the major derivative of taxol found in cells and taxol (paclitaxel) is a well-known natural-source cancer drug.

7-Ethyl-10-Hydroxycamptothecin
Catalog No: CFN90335

7-Ethyl-10-hydroxycamptothecin shows cytotoxicity against breast cancer, it efficiently target-bind to the colon and lungs of mice.

7-Geranyloxy-6-methoxycoumarin
Catalog No: CFN98348

7-Geranyloxy-6-methoxycoumarin shows significant cytotoxicity against three cell lines (A549, SMMC-7721 and BALL-1).

7-Hydroxy-4'-methoxyflavone
Catalog No: CFN70378

Reference standards.

7-Hydroxyaristolochic acid A
Catalog No: CFN90517

7-Hydroxyaristolochic acid A is a natural product from Aristolochia debilis Sieb. et Zucc.

7-Hydroxyflavanone
Catalog No: CFN94487

7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates, it could be useful for the development of a novel respiratory infections treatment.

7-Hydroxyflavone
Catalog No: CFN92768

7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2. It also has excellent antioxidant, anti-inflammatory, and anti-proliferation properties, it may serve as potential protective agents in the treatment of patients with chronic EV71 infection.7-Hydroxyflavone can protect renal cells from NIC-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway; it also can inhibit LPS-induced inflammation via attenuating the production of NO, PGE2 , TNF-α and IL-6.