Hot Products

Paclitaxel
Catalog No: CFN97759

Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibits MT depolymerization, and changes MT dynamics required for mitosis and cell proliferation. Paclitaxel can induce ototoxicity in rats.

Padmatin
Catalog No: CFN97280

Standard reference

Paederoside
Catalog No: CFN92523

Paederoside is a potent deterrent against the beetle was isolated from the aphid.It displays high anti-tumor promoting activity against the Epstein-Barr virus activation.

Paederosidic acid
Catalog No: CFN92524

Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutamic acid in the brain, and it up-regulates expressions of GAD 65, may be a promising future therapeutic agent for treatment of epilepsy.

Paederosidic acid methyl ester
Catalog No: CFN92525

Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.

Paeoniflorigenone
Catalog No: CFN96022

Paeoniflorigenone is a depolarizing neuromuscular blocking agent, being similar to succinylcholine.Paeoniflorigenone is cytotoxic and induces apoptosis selectively in the cancer cell lines. Paeoniflorigenone shows anti-inflammatory effects, it may take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation.

Paeoniflorin
Catalog No: CFN99544

Paeoniflorin, a novel heat shock protein-inducing compound, is mediated by the activation of heat shock transcription factor 1 (HSF1), which has antiallergic, anti-obesity, anti-inflammatory and immunoregulatory effects. Paeoniflorin can activate PI3K/Akt signaling pathway to protect the PC12 cell injury induced by Aβ25-35, it protects thymocytes against irradiation-induced cell damage by scavenging ROS and attenuating the activation of the mitogen-activated protein kinases.

Paeonilactone B
Catalog No: CFN96055

Paeonilactone B is a natural product from Paeonia albiflora.

Paeonilactone C
Catalog No: CFN96056

Paeonilactone C significantly protects primary cultures of rat cortical cells against H2O2-induced neurotoxicity.

Paeonol
Catalog No: CFN98926

Paeonol has anticancer, anti-inflammatory, antioxidant and cardiovascular protective activities, it shows a novel inhibitory role on neuroinflammation, and presents a new candidate agent for the development of therapies for inflammation-related neurodegenerative diseases. Paeonol suppresses lipopolysaccharide-induced inflammatory cytokines in macrophage cells and protects mice from lethal endotoxin shock. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively; it inhibits PGE₂ synthesis and COX-2 expression, and modulates Sirtuin 1, PKCδ and c-Src signaling pathway.