Hot Products

Polpunonic acid
Catalog No: CFN96834

Polpunonic acid is a natural product from Tripterygium wilfordii Hook.f.

Polydatin
Catalog No: CFN99159

Polydatin has antioxidant, anti-inflammatory, neuroprotection and anti-cancer activities, which has favorable potency to develop a hypolipemic and/or hepatoprotective agent in clinic. It is a mitochondria protector for acute severe hemorrhagic shock treatment, the neuronal mitochondrial injury is involved in the genesis of severe shock. Polydatin has a protective effect against ischemia/reperfusion injury in rat heart, the cardioprotection of polydatin is mainly mediated by cNOS which leading to an increase in NO production.

Polygalacic acid
Catalog No: CFN99108

Polygalacic acid may exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of cholinergic activity and neuroinflammation. Polygalacic acid shows significant postingestive effects on Spodoptera littoralis larvae.

Polygalacin D
Catalog No: CFN93351

Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxic effect on RAW 264.7 macrophages, and can suppress induction by LPS of pro-inflammatory cytokines such as prostaglandin E2 (PGE2).

Polygalacin D2
Catalog No: CFN95241

Polygalacin D2 may have antimicrobial activity.

Polygalasaponin E
Catalog No: CFN95138

Reference standards.

Polygalasaponin F
Catalog No: CFN90171

Polygalasaponin F possesses anxiolytic and sedative-hypnotic activities, and has cognition improving and cerebral protective effects. Polygalasaponin F can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Polygalasaponin F can induce long-term potentiation in hippocampal dentate gyrus in anesthetized rats via NMDAR activation mediated by Ca(2+)/calmodulin-dependent kinase II, extracellular signal-regulated kinase and cAMP response element-binding protein signaling pathway.

Polygalasaponin II
Catalog No: CFN91789

Polygalasaponin F analog. Reference standards.

Polygalasaponin V
Catalog No: CFN90650

Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk medicine.

Polygalasaponin XLIX
Catalog No: CFN95117

Reference standards.