Karanjin
Catalog No: CFN93060
Karanjin is a potent Volume-regulated anion channels(VRACs) current inhibitor, the VRAC inhibition might be responsible for its anti-angiogenic effects. Karanjin possesses antioxidant, anti-inflammatory, gastroprotective properties, it can significantly reverse the amnesia induced by diazepam and improve learning and memory of mice in dose and time dependent manner. Karanjin may be effective clinically for cancer pharmacotherapy, it can induce cancer cell death through cell cycle arrest and enhance apoptosis. Karanjin has larvicidal activity toward C. pipiens pallens larvae and A. aegypti larvae. Karanjin also possesses significant antihyperglycemic activity in Streptozotocin-induced diabetic rats and type 2 diabetic db/db mice and protein tyrosine phosphatase-1B may be the possible target for their activity.
