Hot Products

Kaerophyllin
Catalog No: CFN97234

Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression. Kaerophyllin inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.

Kahweol
Catalog No: CFN93033

Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB degradation and inhibiting IkappaB kinase activity. Kahweol also has hepatoprotective and antioxidant effects on carbon tetrachloride-induced liver damage in mice.

Kakkalide
Catalog No: CFN95052

Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects. Kakkalide can inhibit ROS-associated inflammation and ameliorated insulin-resistant endothelial dysfunction by beneficial effects on IRS-1 function.Kakkalide attenuates ethanol-induced gastric injury in mice by inhibiting the infiltration of neutrophils, it also shows protective effects on ethanol-induced lethality and hepatic injury are dependent on its biotransformation by human intestinal microflora.

Kakuol
Catalog No: CFN93222

Kakuol has antifungal activity, it can completely inhibit the mycelial growth of Botrytis cinerea Pers ex Fr and Cladosporium cucumerinum Ellis & Arthur at 50 microg ml(-1) and 30 microg ml(-1), respectively. Kakuol and a derivative analogue are able to inhibit the DNA relaxation mediated by the human enzyme.

Kalopanaxsaponin H
Catalog No: CFN90430

Kalopanaxsaponin H has antidiabetic activity.

Kamebakaurin
Catalog No: CFN91932

Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-κB) p50; it has anti-neuroinflammatory activity via inhibition of c-Jun NH₂-terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity. Kamebakaurin also has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress.

Kanshone B
Catalog No: CFN89423

Kanshone B shows inhibitory activity against LPS-induced NO production with the IC(50) value of 4.6-21.6 uM.

Kanshone H
Catalog No: CFN89349

Reference standards.

Kansuinine A
Catalog No: CFN92863

Kansuinine A possesses analgesic props, it also shows NGF inducing activity.

Kansuinine B
Catalog No: CFN92866

Kansuinine B shows cytotoxic ,and analgesic activities, treatment with kansuinine B and kansuinine A represents a novel method to block the IL-6-induced effects.