Hot Products

Indicine N-oxide
Catalog No: CFN00284

Indicine N-oxide, a pyrrolizidine alkaloid present in the plant Heliotropium indicum, shows promising cytotoxic activity in various tumor models that due to its DNA damaging effects and depolymerization of microtubules.

Indicolactone
Catalog No: CFN95715

Indigo
Catalog No: CFN99992

Indigo and indirubin are potent aryl hydrocarbon receptor ligands present in human urine, the endogenous levels and potencies of indirubin and indigo are such that they activate aryl hydrocarbon receptor (AhR) -mediated signaling mechanisms in vivo . Indigo participates in isolating oxygenase genes, indigo carmine angiography provides visual information on foot perfusion, using indigo dye and synergistic halide additives can inhibit mild steel corrosion in sulphuric acid.

Indirubin
Catalog No: CFN90239

Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM. Indirubin has anticancer, anti-inflammatory,antiviral,anti-allergic contact dermatitis effects. Each indirubin derivative acts on the DNA binding of NF-Y and represses the MDR1 gene promoter with tumor cell-type specificity.Indirubin derivatives have a potential to be used as an adjunct to antiviral therapy for the treatment of severe human H5N1 disease.

Indole
Catalog No: CFN70040

Reference standards.

Indole-3-acetic acid
Catalog No: CFN93308

Indole-3-acetic acid , a well-known phytohormone, can also be a signaling molecule in bacteria and therefore can have a direct effect on bacterial physiology.

Indolelactic acid
Catalog No: CFN95263

Indolelactic acid is a phytochormone.

Ingenol
Catalog No: CFN90187

Ingenol derivatives inhibit proliferation and induce apoptosis in breast cancer cell lines, formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV. Ingenol mebutate is an effective treatment for actinic keratosis.

Ingenol 3-Angelate
Catalog No: CFN90924

Ingenol-3-angelate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo; it activates a broad range of PKC isoforms and induces apoptosis in acute myeloid leukemia cells by activating the PKC isoform PKCdelta. Ingenol-3-angelate suppresses HIV infection of primary CD4+ T cells through down-modulation of cell surface expression of HIV co-receptors. Ingenol-3-angelate emerges as a unique local chemotherapeutic immunostimulatory debulking agent that could be used in conjunction with immunotherapies to promote regression of metastases.

Inokosterone
Catalog No: CFN92515

Inokosterone is an analgesic drug. It also shows high insect moulting hormone activity.