Hot Products

Higenamine HCl
Catalog No: CFN90698

Higenamine HCL is derived from a wide variety of plants and works on the body as a stimulant. It specifically targets the heart muscle to speed up contractions, raising the heart rate.

Hinokiflavone
Catalog No: CFN92007

Hinokiflavone has significant cytotoxicity, it has inhibition of MMP-9.

Hinokiol
Catalog No: CFN98948

Hinokiol has anti-inflammatory activity, it has significant inhibitory effects on 5-hydroxy-eicosa-tetra-enoic acid (5-HETE) and leukotriene B(4) (LTB4) formations. Hinokiol demonstrates potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).

Hinokitiol
Catalog No: CFN93995

Hinokitiol has antibacterial effect , it can inhibit all Staphylococcus aureus isolates with MICs of 1.56-3.13 mg/L, it also has antifungal activity against 51 Malassezia pachydermatis strains, it is an inexpensive and safe treatment with anti-inflammatory and deodorant effects that can be recommended as an effective remedy for canine otitis externa. beta-thujaplicin (Hinokitiol) has ability to extract mitochondrial Mg and the prevention of the effects of beta-thujaplicin by an excess of Mg in the medium, suggests a common mode of action of beta-thujaplicin as a lipophilic chelator of Mg and other divalent cations.

Hirsutanonol
Catalog No: CFN98645

Hirsutanonol has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. Hirsutanonol shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells, it also has chemoprotective effect on human lymphocytes DNA. Hirsutanonol or oregonin as an active ingredient composition for treating atopic dermatitis, hirsutanonol shows significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies.

Hirsutanonol 5-O-glucoside
Catalog No: CFN97513

Reference standards.

Hirsuteine
Catalog No: CFN90615

Hirsuteine exhibits potent neuroprotective effects against glutamate-induced HT22 cell death. Hirsuteine non-competitively antagonizes nicotine-evoked dopamine release by blocking ion permeation through nicotinic receptor channel complexes.

Hirsutenone
Catalog No: CFN98646

Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity.

Hirsutine
Catalog No: CFN90617

Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity.

Hispidin
Catalog No: CFN92660

Hispidin exhibits anti-inflammatory activity through suppressing ROS mediated NF-κB pathway in mouse macrophage cells, it also has anti-cancer activity by inducing both intrinsic and extrinsic apoptotic pathways mediated by ROS in colon cancer cells. Hispidin can inhibit Acrylamide-induced oxidative stress and protect C2C12 myotubes against palmitate-induced oxidative stress by suppressing cleavage of caspase-3, expression of Bax, and NF-κB translocation. Hispidin protects against apoptosis in H9c2 cardiomyoblast cells exposed to hydrogen peroxide through reducing intracellular ROS production, regulating apoptosis-related proteins, and the activation of the Akt/GSK-3β and ERK1/2 signaling pathways.