Hot Products

Gomisin J
Catalog No: CFN90124

Gomisin J is a good substrate of cytochrome P450 3A4(CYP3A4), it has vasodilatory, anti-inflammatory, anti-diabetes, anti-oxidant, and anti-cancer effects, it also has preventive effects on angiotensin II-induced hypertension via an increased nitric oxide bioavailability. Gomisin J has potential benefits in treating nonalcoholic fatty liver disease, it can suppress lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecule. Halogenated gomisin J is a potent inhibitor of the cytopathic effects of human immunodeficiency virus type 1 (HIV-1) on MT-4 human T cells (50% effective dose, 0.1 to 0.5 microM).

Gomisin K1
Catalog No: CFN96724

Gomisin K1 is a natural product from Schizandra chinensis BAILL.

Gomisin L1
Catalog No: CFN96734

(-)-Gomisin L1 induces G2/M arrest and apoptosis in human ovarian cancer cells.

Gomisin L2
Catalog No: CFN96726

Gomisin L2 is a natural product from Schizandra chinensis BAILL.

Gomisin M2
Catalog No: CFN97306

Gomisin M2 is an anti-HIV agent.

Gomisin N
Catalog No: CFN90125

Gomisin N has anti-oxdiant, anti-inflammatory, anti-cancer and anti-hepatitis activities; it produces beneficial sedative and hypnotic bioactivity, which may be mediated by the modification of the serotonergic and GABAergic system. Gomisin N can enhance TNF-α-induced apoptosis by suppressing of NF-κB and EGFR signaling pathways, and potentiate TRAIL-induced apoptosis through ROS-mediated up-regulation of death receptors 4 and 5.

Gomisin O
Catalog No: CFN90751

Gomisin O is a natural product from Schizandra chinensis.

Gomisin S
Catalog No: CFN92716

Reference standards.

Goniothalamin
Catalog No: CFN97803

Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cells, induce apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. Goniothalamin has gastroprotective activity which is inhibited after pre-treatment with NEM (N-ethylmaleimide) and NSAID (non-steroidal anti-inflammatory drugs), highlighting the importance of sulfhydryl compounds and prostaglandins on Goniothalamin activity. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings.

Goshonoside F5
Catalog No: CFN89238

Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.