ent-17-Hydroxykauran-3-one
ent-17-Hydroxy-16α-kauran-3-one shows weak antimicrobial activity when tested against Staphylococcusaureus.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Canadian Journal of Chemistry, 2011, 75(6):801-804.
A new ent-kaurane from the root extract of Chiococcaalba.[Reference:
WebLink]
METHODS AND RESULTS:
A bioassay-guided purification of the methanolic crude extract obtained from the roots of Chiococcaalba (L.) Hitchc. resulted in the isolation of a new, bioactive, metabolite identified as
ent-17-hydroxy-16α-kauran-3-one (ent-17-Hydroxykauran-3-one,1). Elucidation of the new structure was based on analyses of the results obtained from various spectroscopic methods (IR, MS, 1H NMR, and 13C NMR) and chemical transformations.
The stereochemistry at C16 was assigned by comparing both the proton and carbon chemical shifts of C17 with those reported in the literature.
CONCLUSIONS:
The new kaurane showed weak antimicrobial activity when tested against Staphylococcusaureus.
