delta-Amyrin acetate
β-Amyrin acetate and β-Amyrin acetate have antidyslipidemic activity.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Biochem Biophys Res Commun.2017, 482(4):1095-1101
Int J Mol Sci.2021, 22(21):11836.
Mol Biol Rep.2022, doi: 10.1007
In Vivo.2022, 36(3):1136-1143.
J of Ana. Chem.2019, 74(11):1113-1121
Acta Pharm Sin B.2024, 14(4):1772-1786.
Journal of Ginseng Research2019, 10.1016
Mol Med Rep.2022, 26(4):299.
Phytomedicine.2022, 99:153997.
Journal of Chromatography A2020, 460942
Related and Featured Products
Phytomedicine, 2012, 19(8-9):0-0.
β-Amyrin acetate and β-amyrin palmitate as antidyslipidemic agents from Wrightia tomentosa leaves.[Reference:
WebLink]
METHODS AND RESULTS:
The ethanolic extract and fractions of Wrightia tomentosa Roem. & Schult (Apocynaceae) leaves were tested in vivo for their antidyslipidemic activity in high fat diet (HFD) induced dyslipidemic hamsters. Activity guided isolation resulted in identification of antidyslipidemic compounds β-Amyrin acetate(β-AA) and β-Amyrin acetate(β-AP). Compounds β-AA and β-AP decrease the levels of LDL by 36% and 44%, and increase the HDL-C/TC ratio by 49% and 28%, respectively, at a dose of 10 mg/kg. In addition, the isolated compounds β-AA and β-AP showed significant HMG-CoA-reductase inhibition, which was further established by docking studies.
