cis-Moschamine

cis-Moschamine
Product Name cis-Moschamine
CAS No.: 193224-24-7
Catalog No.: CFN94007
Molecular Formula: C20H20N2O4
Molecular Weight: 352.39 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Datura stramonium Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $320/5mg
cis-Moschamine exerts antitumour effects on HeLa, MCF7 and A431 cells.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Phytochem Anal.2022, doi: 10.1002
  • Evid Based Complement Alternat Med.2022, 9767292,2.
  • ACS Omega2020, 5,33,20825-20830
  • Food Chem.2023, 404(Pt A):134517.
  • Metabolites2023, 13(1), 3.
  • Proc Biol Sci.2024, 291(2015):20232578.
  • Polytechnic University of Catalonia2017, 105826
  • Microb Pathog.2019, 131:128-134
  • Molecules.2020, 25(18),4089.
  • Front. Pharmacol.2022, 901563.
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