Triacetonamine
Triacetonamine protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocyte. Triacetonamine can improve the constructile function of heart mus-cles of acute anemia and decrease the content of malodialdehyde (MDA) in the heart muscles.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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Bioresour Technol. 2010 Jun;101(11):4242-5.
Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent.[Pubmed:
20137920]
A sewage sludge sample was pyrolyzed in a drop tube furnace at 500 degrees C and sweeping gas flow rate of 300cm(3)/min.
METHODS AND RESULTS:
Triacetonamine (TAA) was detected with GC/MS as major component in the resulting bio-oil using acetone as the absorption solvent and proven to be a product from the reaction of NH(3) in the bio-oil with the absorption solvent acetone. TAA yield increased with storage time and reached a level about 28.4% (% sludge fed, daf) after 175h. Since the reaction of pure NH(3) with acetone does not proceed, some species in the bio-oil must catalyze the reaction of NH(3) with acetone. TAA was isolated in a high yield (27.9%, daf) and high purity (80.4%) by column chromatography with different solvents, including mixed solvents, as eluants.
CONCLUSIONS:
The study revealed the possibility of sewage sludge as potential resource of TAA.
Supplement to the Journal of Sun Yatsen University, 1994 (6) :9-11.
Protective Effects of Triacetonamine on Acute Ischemia Isolated Rat Heart Muscles[Reference:
WebLink]
Triacetonamine(TAA)could improve the constructile function of heart mus-cles of acute anemia and decrease the content of malodialdehyde (MDA) in the heart muscles. TAA protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK). It also inhibits CaCl2 induced agglomeration of thromocyte.
J Comput Aided Mol Des. 1990 Dec;4(4):403-9.
Theoretical models for the conformations and the protonation of triacetonamine.[Pubmed:
1965442]
In this paper we propose theoretical models for the conformations of Triacetonamine and protonated Triacetonamine (Vincubine, an anticancer chemotherapeutic agent) developed by quantum and molecular mechanics techniques.
METHODS AND RESULTS:
We discuss the theoretical factors which are involved in the stabilization of the conformations calculated by the MNDO, MM2 and COPEANE methods and show the relative percent abundance of each molecular shape. Graphic representations of the conformers are depicted.
