Pipecolinic acid | CAS:535-75-1 | Manufacturer ChemFaces

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Drug Invention Today2019, 12(6):1303-1306

Asian Pac J Cancer Prev.2019, 20(1):65-72

The Journal of Korean Medicine2022, 43(3): 79-93.

Research Square2023, 2883170.

Korean J. of Horticultural Sci. & Tech. 2017, 793-804

Life Sci.2022, 311(Pt A):121157.

Pharmacol Res.2022, 182:106346.

Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083

Inflammation.2015, 38(4):1502-16

South African Journal of Botany2021, 142:114-123.

Clin Chim Acta. 2014 Jan 1;427:79-85.

Investigation and identification of potential biomarkers in human saliva for the early diagnosis of oral squamous cell carcinoma.[Pubmed: 24144867 ]

Oral cancer is 1 of the 6 most common human cancers, with an annual incidence of >300,000 cases worldwide. This study aimed to investigate potential biomarkers in human saliva to facilitate the early diagnosis of oral squamous cell carcinoma (OSCC).
METHODS AND RESULTS:
Unstimulated whole saliva obtained from OSCC patients (n=30) and apparently healthy individuals (n=30) were assayed with ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) in hydrophilic interaction chromatography mode. The data were analyzed using a nonparametric Mann-Whitney U test, logistic regression, and the receiver operating characteristic (ROC) to evaluate the predictive power of each of 4 biomarkers, or combinations of biomarkers, for OSCC screening. Four potential salivary biomarkers demonstrated significant differences (P<0.05) in concentrations between patients at stages I-II and the healthy individuals. The area under the curve (AUC) values in control vs OSCC I-II mode based on choline, betaine, Pipecolinic acid, and l-carnitine were 0.926, 0.759, 0.994, and 0.708, respectively. Four salivary biomarkers in combination yielded satisfactory accuracy (0.997), sensitivity (100%), and specificity (96.7%) in distinguishing OSCC I-II from control.
CONCLUSIONS:
Salivary metabolite biomarkers for the early diagnosis of OSCC were verified in this study. The proposed approach is expected to be applied as a potential technique of preclinical screening of OSCC.

Product Name	Pipecolinic acid
CAS No.:	535-75-1
Catalog No.:	CFN80270
Molecular Formula:	C₆H₁₁NO₂
Molecular Weight:	129.07 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Gleditsia caspica.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$30/20mg