1-Methoxycarbonyl-beta-carboline-N-oxide | CAS:74690-74-7

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PREPARATIVE ISOLATION AND PURIFICATION OF ALKALOIDS FROM PICRASMA QUASSIODES (D. DON) BENN. BY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY.[Reference: WebLink]

METHODS AND RESULTS:
By using a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (2:2:2:2, v/v/v/v), a high-speed counter-current chromatography technique was successfully used for isolation and purification of three alkaloids from Picrasma quassiodes (D. Don) Benn. for the first time. A total of 22.1 mg of 3-methylcanthin-2,6-dione, 4.9 mg of 4-methoxy-5-hydroxycanthin-6-one and 1.2 mg of 1-methoxycarbonyl-β-carboline were obtained from 100 mg of crude extract of Picrasma quassiodes (D. Don) Benn. in less than 5 hr, with purities of 89.30%, 98.32%, and 98.19%, respectively.
CONCLUSIONS:
The target compounds were identified by ESI-MS, 1H NMR, and 13C NMR.

Product Name	1-Methoxycarbonyl-beta-carboline-N-oxide
CAS No.:	74690-74-7
Catalog No.:	CFN95023
Molecular Formula:	C₁₃H₁₀N₂O₃
Molecular Weight:	242.2 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Yellow powder
Source:	The barks of Picrasma quassioides
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$318/5mg