Topazolin

Topazolin
Product Name Topazolin
CAS No.: 109605-79-0
Catalog No.: CFN96520
Molecular Formula: C21H20O6
Molecular Weight: 368.39 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Targets: Antifection
Source: The roots of Yellow Lupin.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Topazolin has weak fungitoxic activity, it displays significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 ug/mL, it also shows in vitro free radical scavenging activities with IC50 values in the range of 0.18-0.56 mg/mL.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Korean Journal of Pharmacognosy2018, 49(1):76-83
  • Pharmaceuticals (Basel).2022, 15(8):982.
  • Molecules.2022, 27(19):6651.
  • Pak J Pharm Sci.2019, 32(6):2879-2885
  • Revista Brasileira de Farmacognosia2024, 34:1276-1286.
  • Nutrients2023, 15(18), 4016.
  • J Ethnopharmacol.2017, 196:75-83
  • Fitoterapia.2024, 175:105955.
  • Acta Pharm Sin B.2024, 14(4):1772-1786.
  • Applied Biological Chemistry2022, 65(77).
  • Isoanhydroicaritin

    Catalog No: CFN93597
    CAS No: 28610-30-2
    Price: Inquiry(manager@chemfaces.com)
    Icaritin

    Catalog No: CFN98527
    CAS No: 118525-40-9
    Price: $60/20mg
    Anhydroicaritin

    Catalog No: CFN98526
    CAS No: 38226-86-7
    Price: $60/20mg
    Citrusinol

    Catalog No: CFN91888
    CAS No: 112516-43-5
    Price: Inquiry(manager@chemfaces.com)
    Broussoflavonol B

    Catalog No: CFN92774
    CAS No: 99217-70-6
    Price: Inquiry(manager@chemfaces.com)
    8-Lavandulylkaempferol

    Catalog No: CFN96053
    CAS No: 883859-83-4
    Price: Inquiry(manager@chemfaces.com)
    Kushenol C

    Catalog No: CFN92391
    CAS No: 99119-73-0
    Price: $468/10mg
    Licoflavonol

    Catalog No: CFN96515
    CAS No: 60197-60-6
    Price: $318/5mg
    Topazolin

    Catalog No: CFN96520
    CAS No: 109605-79-0
    Price: Inquiry(manager@chemfaces.com)
    Cudraflavone B

    Catalog No: CFN91905
    CAS No: 19275-49-1
    Price: Inquiry(manager@chemfaces.com)
    Fitoterapia. 2015 Jun;103:289-93.
    Prenylated polyphenolic compounds from Glycyrrhiza iconica and their antimicrobial and antioxidant activities.[Pubmed: 25963162]

    METHODS AND RESULTS:
    A new prenylated isoflavan, iconisoflavan (1), and a new prenylated isoflav-3-ene, iconisoflaven (2) were isolated from the roots of Glycyrrhiza iconica together with four known ones namely (3S)-licoricidin (3), licorisoflavan A (4), Topazolin (5) and glycycoumarin (6). The structures were elucidated on the basis of extensive spectroscopic analysis including 1D and 2D NMR as well as HR-MS. Furthermore, the absolute configurations of compounds 1, 3 and 4 were established by electronic circular dichroism (ECD). All the isolated compounds (1-6) were evaluated for their in vitro antimicrobial activities against five pathogenic bacteria and one yeast (Candida albicans) using an in vitro microdilution method.
    CONCLUSIONS:
    Compounds 1 and 3-5 displayed significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 μg/mL. Additionally, all compounds were screened for their in vitro free radical scavenging activities using an in vitro microdilution DPPH assay spectrofotometrically. The tested compounds exhibited IC50 values in the range of 0.18-0.56 mg/mL, suggesting an activity comparable with that of ascorbic acid (IC50: 0.07 mg/mL). To the best of our knowledge, the present study constitutes the first phytochemical and bioactivity investigation on G. iconica.
    Agricultural & Biological Chemistry, 2006, 51(4):1039-1044.
    New 3-Methoxyflavones in the Roots of Yellow Lupin (Lupinus luteus L. cv. Topaz)[Reference: WebLink]

    METHODS AND RESULTS:
    An isopropenyl ( = 3,3-dimethylallyl) 3-methoxyflavone (1) and its hydrate (5) were isolated from the roots of yellow lupin, Lupinus luteus L. cv. Topaz. Their structures were unambiguously determined to be 5,7,4′-trihydroxy-3-methoxy-6-(3,3-dimethylallyl)flavone (1) and 5,7,4′-trihydroxy-6-(3-hydroxy-3-methylbutyl)-3-methoxyflavone (5) by a combination of chemical and spectroscopic methods, and the new flavones were named Topazolin and Topazolin hydrate, respectively.
    CONCLUSIONS:
    Antifungal tests against the growth of Cladosporium herbarum indicated that, in spite of its phenolic nature and the possession of an isopentenyl sidechain, Topazolin (1) had only weak fungitoxic activity.
    Isonemerosin

    Catalog No: CFN95008
    CAS No: 181524-79-8
    Price: $268/20mg
    Dihydrolicoisoflavone

    Catalog No: CFN95073
    CAS No: 164163-92-2
    Price: $333/5mg
    Polygalin C

    Catalog No: CFN95118
    CAS No: 934768-05-5
    Price: $288/5mg
    Ampelopsin G

    Catalog No: CFN95148
    CAS No: 151487-09-1
    Price: $318/5mg
    New compound 9

    Catalog No: CFN95342
    CAS No: N/A
    Price: $413/5mg
    Tortoside B (Manglieside E)

    Catalog No: CFN95390
    CAS No: 190655-17-5
    Price: $413/5mg
    5-Demethylsinensetin

    Catalog No: CFN95415
    CAS No: 21763-80-4
    Price: $318/10mg
    Giganteone A

    Catalog No: CFN95481
    CAS No: 460337-13-7
    Price: $318/5mg
    Quercetin 3,5-O-diglucoside

    Catalog No: CFN95486
    CAS No: 206257-35-4
    Price: $368/10mg
    Ganosinensic acid C

    Catalog No: CFN95567
    CAS No: 2231756-23-1
    Price: $413/5mg