Sophorabioside

Sophorabioside
Product Name Sophorabioside
CAS No.: 2945-88-2
Catalog No.: CFN90958
Molecular Formula: C27H30O14
Molecular Weight: 578.52 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The seeds of Sophora japonica.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $288/10mg
Sophorabioside is a natural product from Sophora japonica.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Journal of Phytopathology2021, 169,Issue11-12.
  • Biomed Pharmacother.2021, 137:111362.
  • Oncotarget.2017, 8(64):108006-108019
  • Heliyon.2023, 9(12):e22932.
  • In Vitro Cellular & Developmental Biology - Plant 2021, 57:874¨C882.
  • Food Funct.2022, 13(13):6923-6933.
  • Chinese Journal of Tissue Engineering Research2024, 28(8):1149-1154.
  • J Ethnopharmacol.2020, 269:113752.
  • Molecules.2021, 26(16):4722.
  • Brain Res Bull.2024, 218:111103.
  • Hydrangenol

    Catalog No: CFN98745
    CAS No: 480-47-7
    Price: Inquiry(manager@chemfaces.com)
    Harpagide

    Catalog No: CFN98148
    CAS No: 6926-08-5
    Price: $70/20mg
    Mogroside IIe

    Catalog No: CFN92191
    CAS No: 88901-38-6
    Price: $218/10mg
    Bavachinin

    Catalog No: CFN98006
    CAS No: 19879-30-2
    Price: $80/20mg
    Aromadendrin

    Catalog No: CFN98736
    CAS No: 480-20-6
    Price: $318/20mg
    PLoS One. 2014 Jun 3;9(6):e98559.
    Isolation of antiosteoporotic compounds from seeds of Sophora japonica.[Pubmed: 24892557]
    Chemical investigation of Sophora japonica seeds resulted in the isolation of seven metabolites identified as: genistin (1), sophoricoside (2), Sophorabioside (3), sophoraflavonoloside (4), genistein 7,4'-di-O-β-D-glucopyransoide (5), kaempferol 3-O-α-L-rhamnopyranosyl(1 → 6)β-D-glucopyranosyl(1 → 2)β-D-glucopyranoside (6) and rutin (7).
    METHODS AND RESULTS:
    Compounds 1, 2 and 5 showed significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range. Compounds 1 and 2 showed minimal cell membrane damaging effect using LDH leakage assay. Accordingly, compound 2 (sophoricoside, (SPH)) was selected for further in-vivo studies as a potential anti-osteoporosis agent. The anti-osteoporotic effect of SPH was assessed in ovarectomized (OVX) rats after oral administration (15 mg/kg and 30 mg/kg) for 45 days compared to estradiol (10 µg/kg) as a positive control. Only in a dose of 30 mg/kg, SPH regained the original mechanical bone hardness compared to normal non-osteoporotic group. However, SPH (15 mg/kg) significantly increased the level of alkaline phosphatase (ALP) to normal level. Treatment with SPH (30 mg/kg) increased the level of ALP to be higher than normal group. SPH (15 mg/kg) did not significantly increase the serum level of osteocalcin (OC) compared to OVX group. On the other hand, treatment with SPH (30 mg/kg) significantly increased the level of OC to 78% higher than normal non-ovarectomized animals group. In addition, SPH (15 mg/kg) decreased the bone resorption marker, acid phosphatase (ACP) to normal level and SPH (30 mg/kg) further diminished the level of serum ACP.
    CONCLUSIONS:
    Histopathologically, sophoricoside ameliorated the ovarectomy induced osteoporosis in a dose dependent manner. The drug showed thicker bony trabeculae, more osteoid, and more osteoblastic rimming compared to OVX group.
    Decursitin D

    Catalog No: CFN95002
    CAS No: 245446-61-1
    Price: $388/5mg
    Suchilactone

    Catalog No: CFN95010
    CAS No: 50816-74-5
    Price: $338/5mg
    9-O-Acetyl-fargesol

    Catalog No: CFN95031
    CAS No: 449172-61-6
    Price: $413/5mg
    3-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin

    Catalog No: CFN95154
    CAS No: 148210-00-8
    Price: $413/5mg
    Atractylochromene

    Catalog No: CFN95162
    CAS No: 203443-33-8
    Price: $318/10mg
    9,11-Dehydro-beta-boswellic acid

    Catalog No: CFN95335
    CAS No: 471-65-8
    Price: $318/5mg
    New compound 8

    Catalog No: CFN95341
    CAS No: N/A
    Price: $318/5mg
    Narirutin 4'-glucoside

    Catalog No: CFN95421
    CAS No: 17257-22-6
    Price: $318/10mg
    Symplocoside

    Catalog No: CFN95552
    CAS No: 76502-76-6
    Price: $318/5mg
    Resinacein D

    Catalog No: CFN95591
    CAS No: 2231061-47-3
    Price: $413/5mg