Schleicheol 1
Schleicheol 1 has antitumor activity, it possesses inhibitory activity against SGC-7901 cell line.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Journal of Tropical & Subtropical Botany, 2015 , 23 (3) :329-33.
Studies on Chemical Compositions and Cytotoxicities from Roots of Aphanamixis grandifolia Bl[Reference:
WebLink]
METHODS AND RESULTS:
In order to understand the antitumor active ingredients of Aphanamixis grandifolia Bl., nine compounds were isolated from 95% ethanol extract of its roots. They were identifi ed as 7-hydroxycadalene(1), dregeana-1(2), 4-oxopinoresinol(3), 4-ketopinoresinol(4), 6-deoxyjacareubin(5), Schleicheol 1(6), stigmasterol(7), β-sitosterol(8), and daucosterol(9) on the basis of spectral data. Compounds 1– 6 were isolated from the genus Aphanamixis for the fi rst time, and the 13 C NMR spectral data of compound 1 was reported for the fi rst time.
CONCLUSIONS:
Compounds 1 and 5 showed inhibition of the proliferation of K562 cell line, and compounds 1, 5 and 6 possessed inhibitory activity against SGC-7901 cell line.
