Pseudolaric acid A
Pseudolaric acid A and -B can inhibit the growth of particular cell type.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Planta Med. 1990 Aug;56(4):383-5.
The cytotoxic principles of Pseudolarix kaempferi: pseudolaric acid-A and -B and related derivatives.[Pubmed:
2236294]
METHODS AND RESULTS:
Pseudolaric acid A and Pseudolaric acid B, the novel diterpene acids isolated from Pseudolarix kaempferi, and their related derivatives have been tested for cytotoxicity against KB, A-549, HCT-8, P-388, and L-1210 tumor cells. The results showed that Pseudolaric acid A and Pseudolaric acid B demonstrated potent cytotoxicity.
CONCLUSIONS:
The selectivity of Pseudolaric acid A and Pseudolaric acid B which inhibit the growth of particular cell types within the disease-oriented human cancer cell line panels is discussed.
