Periglaucine B

Periglaucine B
Product Name Periglaucine B
CAS No.: 1025023-05-5
Catalog No.: CFN96748
Molecular Formula: C20H23NO6
Molecular Weight: 373.40 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Targets: HBV
Source: The aerial parts of Pericampylus glaucus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Periglaucine B can inhibit hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Molecules.2024, 29(5):1050.
  • Life (Basel).2023, 13(2):457.
  • BMB Rep.2020, 53(4):218-222.
  • BMC Complement Altern Med.2019, 19(1):339
  • Evid Based Complement Alternat Med.2017, 2017:9764843
  • Molecules.2018, 23(3):E615
  • J Microbiol Biotechnol.2022, 32(2):141-148.
  • PLoS One.2021, 16(6):e0248479.
  • Development.2024, 151(20):dev202518.
  • Food Chem.2020, 332:127412
  • Sinomenine HCl

    Catalog No: CFN99561
    CAS No: 6080-33-7
    Price: $40/20mg
    Sinomenine N-oxide

    Catalog No: CFN95807
    CAS No: 1000026-77-6
    Price: $318/10mg
    Fenfangjine G

    Catalog No: CFN92332
    CAS No: 205533-81-9
    Price: Inquiry(manager@chemfaces.com)
    16-Oxoprometaphanine

    Catalog No: CFN98993
    CAS No: 58738-31-1
    Price: Inquiry(manager@chemfaces.com)
    Prometaphanine

    Catalog No: CFN97167
    CAS No: 6858-85-1
    Price: Inquiry(manager@chemfaces.com)
    Prostephanaberrine

    Catalog No: CFN97858
    CAS No: 105608-27-3
    Price: Inquiry(manager@chemfaces.com)
    Acutumine

    Catalog No: CFN95808
    CAS No: 17088-50-5
    Price: $318/5mg
    Sinoacutine

    Catalog No: CFN98640
    CAS No: 4090-18-0
    Price: Inquiry(manager@chemfaces.com)
    Dihydrooxoepistephamiersine

    Catalog No: CFN98831
    CAS No: 51804-69-4
    Price: Inquiry(manager@chemfaces.com)
    Dihydroepistephamiersine 6-acetate

    Catalog No: CFN98965
    CAS No: 57361-74-7
    Price: Inquiry(manager@chemfaces.com)
    J Nat Prod. 2008 May;71(5):760-3.
    Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus.[Pubmed: 18396905]

    METHODS AND RESULTS:
    Four new hasubanane-type alkaloids, periglaucine A, Periglaucine B, periglaucine C, periglaucine D (1-4), and three known alkaloids, norruffscine (5), (-)-8-oxotetrahydropalmatine (6), and (-)-8-oxocanadine (7), were isolated from the aerial parts of Pericampylus glaucus. Their structures were elucidated on the basis of extensive NMR and EIMS data, and that of periglaucine A (1) was confirmed by single-crystal X-ray diffraction.
    CONCLUSIONS:
    Alkaloids 1-4 inhibited hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells. (-)-8-Oxotetrahydropalmatine (6) possessed a high selectivity index (SI = 22.4) for HBsAg secretion of the Hep G2.2.15 cell line with an IC(50) value of 0.14 mM. Norruffscine (5) and (-)-8-oxotetrahydropalmatine (6) exhibited inhibitory activity against human immunodeficiency virus (HIV-1) with EC(50) values of 10.9 and 14.1 microM in C8166 cells (SI = 45.7 and 18.8), respectively.
    Shancigusin I

    Catalog No: CFN95061
    CAS No: 1435488-35-9
    Price: Inquiry(manager@chemfaces.com)
    Suspenoidside B

    Catalog No: CFN95071
    CAS No: 2161432-08-0
    Price: $413/5mg
    Licoarylcoumarin

    Catalog No: CFN95072
    CAS No: 125709-31-1
    Price: $413/5mg
    Emodin-8-O-beta-gentiobioside

    Catalog No: CFN95132
    CAS No: 66466-22-6
    Price: $368/5mg
    Rhamnocitrin 3-apiosyl-(1->2)-glucoside

    Catalog No: CFN95145
    CAS No: 148031-68-9
    Price: $318/10mg
    Fuzitine

    Catalog No: CFN95337
    CAS No: 142287-96-5
    Price: $318/5mg
    Apigenin 7-[rhamnosyl-(1->2)-galacturonide]

    Catalog No: CFN95352
    CAS No: 124167-97-1
    Price: $318/10mg
    Pinocembroside

    Catalog No: CFN95444
    CAS No: 75829-43-5
    Price: $118/20mg
    Neoorthosiphol A

    Catalog No: CFN95447
    CAS No: 243448-72-8
    Price: $318/10mg
    Mahuannin J

    Catalog No: CFN95533
    CAS No: N/A
    Price: $318/5mg