Pericyclivine
Pericyclivine is a natural product from Catharanthus roseus.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Pharm Sci. 1978 Feb;67(2):249-51.
Plant anticancer agents V: new bisindole alkaloids from Tabernaemontana johnstonii stem bark.[Pubmed:
621649]
METHODS AND RESULTS:
The isolation and structure elucidation of the three new bisindole alkaloids, gabunamine, tabernamine, and 19,20-epoxyconoduramine, from Tabernaemontana johnstonii stem bark are described. The isolation of the seven known alkaloids, conodurine, conoduramine, gabunine, isovacangine, ibogamine, Pericyclivine, and perivine, from the same source also is noted.
CONCLUSIONS:
The alkaloids gabunamine, gabunine, and tabernamine showed significant cytotoxicity against the P-388 cell culture system.
