Officinalisinin I

Officinalisinin I
Product Name Officinalisinin I
CAS No.: 57944-18-0
Catalog No.: CFN90692
Molecular Formula: C45H76O19
Molecular Weight: 921.07 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The rhizomes of Anemarrhena asphodeloides Bunge
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $248/20mg
Officinalisinin Ⅰcan effectively reduce the blood glucose and protect nerve injuryin diabetic mice.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Biochem Mol Toxicol.2020, 34(7):e22489.
  • Pharmacol Res.2020, 161:105205.
  • Molecules.2017, 22(2)
  • TCI CO.2019, US20190151257A1
  • Int J Mol Sci.2022, 23(10):5468.
  • Appl. Sci.2021, 11(1),14.
  • Molecules.2024, 29(3):671.
  • Exp Parasitol.2015, 153:160-4
  • Toxicol In Vitro.2024, 99:105876.
  • Journal of Life Science2017, 233-240
  • 25S-Tupistroside E

    Catalog No: CFN95890
    CAS No: N/A
    Price: $318/20mg
    25R-Tupistroside E

    Catalog No: CFN95891
    CAS No: 1448639-95-9
    Price: $318/20mg
    Protodioscin

    Catalog No: CFN99517
    CAS No: 55056-80-9
    Price: $50/20mg
    Methyl protodioscin

    Catalog No: CFN99585
    CAS No: 54522-52-0
    Price: $100/20mg
    Protodeltonin

    Catalog No: CFN93008
    CAS No: 94992-08-2
    Price: Inquiry(manager@chemfaces.com)
    Pseudoprotogracillin

    Catalog No: CFN93038
    CAS No: 637349-03-2
    Price: Inquiry(manager@chemfaces.com)
    Protogracillin

    Catalog No: CFN93054
    CAS No: 54848-30-5
    Price: Inquiry(manager@chemfaces.com)
    Methyl protogracillin

    Catalog No: CFN80084
    CAS No: 54522-53-1
    Price: $318/10mg
    Polyphyllin G

    Catalog No: CFN99955
    CAS No: 76296-75-8
    Price: Inquiry(manager@chemfaces.com)
    Parisaponin I

    Catalog No: CFN90702
    CAS No: 561007-63-4
    Price: Inquiry(manager@chemfaces.com)
    China Journal of Traditional Chinese Medicine & Pharmacy, 2017 (2) :782-785.
    Study on hypoglycemic mechanism and central nerve protection of Officinalisinin Ⅰ in Rhizoma Anemarrhenae[Reference: WebLink]
    To study the hypoglycemic effect of Officinalisinin Ⅰin Rhizoma Anemarrhenae on diabetes, and discuss the hypoglycemic mechanism and protective effect on diabetic nephropathy.
    METHODS AND RESULTS:
    Glucose tolerance was measured in model mice induced by oral administration of alloxan.Inhibition of glycosidase activity was tested in vitro.GLP-1 was detected after fasting in diabetic mice.The levels of BDNF and GSH-PX in serum were detected by enzyme-linked immunosorbent assay(ELISA) after 20 days of medication.Officinalisinin I has the functions of lowering blood glucose and significantly improving the glucose tolerance of diabetic mice.In the experiment, the glycosidase inhibitor pathway was eliminated, andby promoting the generation of GLP-1 and BDNF and increasing the activity of GSH-PX Officinalisinin I achieves the hypoglycemic and neuroprotective effect.
    CONCLUSIONS:
    Officinalisinin I can effectively reduce the blood glucose and protect nerve injuryin diabetic mice.
    3,3',4',5,6,7,8-heptamethoxyflavone

    Catalog No: CFN95021
    CAS No: 1178-24-1
    Price: $268/10mg
    3'-Angeloyloxy-4'-senecioyloxy-2',3'-dihydrooroselol

    Catalog No: CFN95123
    CAS No: 1221686-60-7
    Price: $398/5mg
    Polygalacin D2

    Catalog No: CFN95241
    CAS No: 66663-92-1
    Price: $413/5mg
    11-Deoxyisomogroside V

    Catalog No: CFN95288
    CAS No: 1628293-32-2
    Price: $368/10mg
    Notoginsenoside L13

    Catalog No: CFN95332
    CAS No: 2485859-56-9
    Price: $318/5mg
    Violanone

    Catalog No: CFN95385
    CAS No: 52250-38-1
    Price: $318/10mg
    5,6,7,3',4'-Pentamethoxyflavanone

    Catalog No: CFN95394
    CAS No: 104193-93-3
    Price: $318/5mg
    Methyl nomilinate

    Catalog No: CFN95576
    CAS No: 77887-51-5
    Price: $318/5mg
    Mahuannin E

    Catalog No: CFN95585
    CAS No: 1173887-70-1
    Price: $318/5mg
    11-Keto-ganoderic acid DM

    Catalog No: CFN95593
    CAS No: N/A
    Price: $413/5mg