Odoriflavene
Odoriflavene has antioxidant activity, and it also shows inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation. Odoriflavene shows cytotoxic activity against a SH-SY5Y cell line in vitro.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Ethnopharmacol.2022, 291:115159.
Front Pharmacol.2021, 12:764297.
Molecules.2021, 26(12):3652.
Int J Mol Sci.2022, 23(24):16000.
Biomed Sci Letters.2020, 26:319-326
Chem Biol Interact.2018, 290:44-51
J Cachexia Sarcopenia Muscle.2022, 13(6):3149-3162.
J Ethnopharmacol.2019, 241:112025
Molecules.2021, 26(6):1635.
Acta horticulturae2017, 1158:257-268
Related and Featured Products
Food Chemistry, 2007, 104(2):715-720.
Antioxidant activities of compounds isolated from Dalbergia odorifera T. Chen and their inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation.[Reference:
WebLink]
METHODS AND RESULTS:
Four compounds were isolated from the root of Dalbergia odorifera T. Chen and identified by chemical and spectroscopic methods as 2′-O-methyl-isoliquiritigenin (1), Odoriflavene (2), 5′-methoxy-vestitol (3) and formononetin (4). Their antioxidant activities were investigated in lard by the oxidative stability instrument; their inhibitory effects on the decrease of glutathione level of rat lens induced by UV irradiation were studied using a rat lens UV-damage model, and their in vitro cytotoxicity was measured on human SH-SY5Y neuroblastoma cells.
CONCLUSIONS:
Results indicated that all four compounds had obvious antioxidant effects, while none of them showed any synergistic effects on butylated hydroxytoluene or α-tocopherol. When FeCl3 (4.0 μM) was added, the antioxidant activities of the four compounds markedly decreased. The inhibitory effects of compounds 1, 2 and 4 on the decrease of glutathione level of rat lens induced by UV irradiation were comparable to that of α-tocopherol.All four compounds showed cytotoxic activity when evaluated against a SH-SY5Y cell line in vitro.
Chem Pharm Bull (Tokyo). 1992 Sep;40(9):2452-7.
Inhibitors of prostaglandin biosynthesis from Dalbergia odorifera.[Pubmed:
1446367]
METHODS AND RESULTS:
The root heartwood of Dalbergia odorifera T. Chen (Leguminosae) is a Chinese medicinal drug (Japanese name koshinko) used for a stagnant blood syndrome (stagnation of disordered blood; Japanese, oketsu). In addition to 10 known compounds, five new phenolic compounds, isomucronustyrene and hydroxyobtustyrene (cinnamylphenols), (+)-isoduartin (isoflavan), Odoriflavene (isoflav-3-ene) and (-)-odoricarpan (pterocarpan) were isolated and their structures were elucidated on the basis of chemical and spectroscopic methods.
CONCLUSIONS:
Of the fifteen compounds isolated, cinnamylphenols, isoflavans, isoflavene and benzoic acid derivative significantly inhibited prostaglandin biosynthesis as well as platelet aggregation induced by arachidonic acid.
