7-Prenylumbelliferone
7-Prenylumbelliferone is a natural product from Heracleum dissectum.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Front Pharmacol.2021, 12:744624.
Bioorg Chem.2024, 152:107720.
Separations2021, 8(1), 1.
Fitoterapia.2022, 157:105130.
Biochem Pharmacol. 2023, 210:115463.
Biomed Pharmacother.2022, 145:112474.
Food Sci Biotechnol.2024, 34(3):611-620.
Antioxidants (Basel).2021, 10(1):112.
Journal of Medical Sciences2024, 44(5):p 222-227.
Current Enzyme Inhibition2023, 19(1):55-64(10)
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Phytochemistry, 1973 , 12 (7) :1657-67.
Furanocoumarin biosynthesis in Ruta graveolens cell cultures[Reference:
WebLink]
The biosynthetic routes to four linear furanocoumarins—psoralen, xanthotoxin, bergapten. isopimpinellin-co-occurring in Ruta graveolens cell cultures have been investigated with six 14C-labelled compounds.
METHODS AND RESULTS:
Mevalonic acid was only poorly incorporated, in contrast to umbelliferone. In support of previous suggestions, 7-demethylsuberosin and (±)-marmesin were very good precursors of the linear furanocoumarins. 7-O-Prenylumbelliferone(7-Prenylumbelliferone) also was fairly well utilized, but this was probably owing to a prior ether cleavage yielding umbelliferone. Psoralen was well incorporated into bergapten and xanthotoxin, but not into the dimethoxylated isopimpinellin. Differences exist between the organized plant and its cell culture in terms of metabolic products and, by implication, precursor utilization. S(+)-Marmesin was obtained in small quantity from an acid-hydrolysable conjugate present in the culture medium.
CONCLUSIONS:
Syntheses of [2-14C]7-demethylsuberosin, [2-14C]osthenol, [2-14C]7-O-prenylumbelliferone, [3-14C] (±)-marmesin, and [3-14C]psoralen are described, as well as an improved method for separation of furanocoumarin mixtures by TLC and GLC.
