4-Methoxycoumarine

4-Methoxycoumarine
Product Name 4-Methoxycoumarine
CAS No.: 20280-81-3
Catalog No.: CFN94403
Molecular Formula: C10H8O3
Molecular Weight: 176.17 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The herbs of Guazuma ulmifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $158/20mg
4-Methoxycoumarin has antitumour effects.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Journal of Mushroom2023, 21(4):215-221.
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • Int J Pharm.2022, 618:121636.
  • Plants (Basel).2021, 10(11):2317.
  • Int J Food Sci Nutr.2019, 70(7):825-833
  • Int J Mol Sci.2023, 24(4):3682.
  • J Bone Miner Res.2017, 32(12):2415-2430
  • Phytother Res.2020, 34(4):788-795.
  • Toxicol Res.2019, 35(4):371-387
  • Geroscience.2024, 01207-y.
  • Skimmin

    Catalog No: CFN97505
    CAS No: 93-39-0
    Price: $238/20mg
    Apiosylskimmin

    Catalog No: CFN90311
    CAS No: 103529-94-8
    Price: $656/10mg
    Hymexelsin

    Catalog No: CFN95849
    CAS No: 117842-09-8
    Price: $368/5mg
    Umbelliferone 7-O-rutinoside

    Catalog No: CFN95431
    CAS No: 135064-04-9
    Price: $318/10mg
    7-Prenylumbelliferone

    Catalog No: CFN90825
    CAS No: 10387-50-5
    Price: $138/20mg
    Auraptene

    Catalog No: CFN98787
    CAS No: 495-02-3
    Price: $60/20mg
    Marmin

    Catalog No: CFN99621
    CAS No: 14957-38-1
    Price: $218/20mg
    Marmin acetonide

    Catalog No: CFN98408
    CAS No: 320624-68-8
    Price: Inquiry(manager@chemfaces.com)
    7'-O-Ethylmarmin

    Catalog No: CFN97584
    CAS No: N/A
    Price: Inquiry(manager@chemfaces.com)
    Excavatin M

    Catalog No: CFN98274
    CAS No: 250293-31-3
    Price: Inquiry(manager@chemfaces.com)
    Melanoma Research, 1999, 9(3):243-248.
    Cytostatic activity of coumarin metabolites and derivatives in the B16-F10 murine melanoma cell line.[Reference: WebLink]
    Coumarin has antitumour effects in vivo and cytostatic effects in vitro. Its half-life in humans is short (1-1.5 h) and the monohydroxylated biotransformation products have significantly longer half-lives. One or several of these products may thus be responsible for the antitumoral effects.
    METHODS AND RESULTS:
    We have assayed the in vitro cytostatic activity of five monohydroxylated coumarins (3-, 4-, 6-, 7- and 8-monohydroxycoumarin), their acetates and methyl-ethers. Murine melanoma cells (cell line B16-F10) and murine fibroblasts (B82) were exposed to the test compounds at concentrations between 10 and 160 microg/ml. The cytostatic effects were estimated by reduction of the tetrazolium dye MTT. In the melanoma cells, some of the compounds inhibited growth after exposure for 1 day. In contrast, coumarin inhibited growth to a smaller extent, and only after exposure for 3 days. The most active compounds (3-acetoxycoumarin, 4-methoxycoumarin(4-Methoxycoumarine) and 6-hydroxycoumarin), as well as coumarin, were also assayed in murine fibroblasts.
    CONCLUSIONS:
    The cytostatic effects of 4-methoxycoumarin(4-Methoxycoumarine) and 6-hydroxycoumarin were less pronounced in fibroblasts than in melanoma cells. Our observations suggest that these compounds may have a greater therapeutic margin.
    cis-Mulberroside A

    Catalog No: CFN95006
    CAS No: 166734-06-1
    Price: $368/10mg
    Selaginellin

    Catalog No: CFN95030
    CAS No: 941269-84-7
    Price: $338/5mg
    Andrographidine A

    Catalog No: CFN95210
    CAS No: 113963-37-4
    Price: $318/10mg
    6-Hydroxy-7-methoxydihydroligustilide

    Catalog No: CFN95289
    CAS No: 210036-09-2
    Price: $318/5mg
    Eschweilenol C

    Catalog No: CFN95363
    CAS No: 211371-02-7
    Price: $318/10mg
    Lariciresinol 4-O-glucoside

    Catalog No: CFN95389
    CAS No: 143663-00-7
    Price: $318/5mg
    Dihydrophaseic acid 4'-O-beta-D-glucopyranoside

    Catalog No: CFN95393
    CAS No: 78914-56-4
    Price: $318/5mg
    5-O-Coumaroylquinic acid

    Catalog No: CFN95507
    CAS No: 32451-86-8
    Price: $318/5mg
    Odontoside

    Catalog No: CFN95530
    CAS No: 20300-50-9
    Price: $318/5mg
    Octyl 3-(4-hydroxyphenyl)prop-2-enoate

    Catalog No: CFN95563
    CAS No: N/A
    Price: $318/5mg