Nortropacocaine
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Pharm Sci. 1979 Jun;68(6):788-90.
Nortropacocaine hydrochloride conformation in aqueous and hydrophobic media.[Pubmed:
458585]
The Nortropacocaine hydrochloride PMR spectra in deuterium oxide and in deuterochloroform differed markedly.
METHODS AND RESULTS:
A detailed conformational analysis using vicinal 1H-1H coupling constants revealed the molecular conformation to be identical in both solvents. The preferred conformation was one in which the piperidine component existed as a deformed chair.
The spectral differences were due to a decreased deshielding of the protonated nitrogen on the neighboring bicyclic ring protons, resulting in chemical shift changes.
