Brugine
Brugine is a natural product from Bruguiera sexangula.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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FASEB J.2019, 33(2):2026-2036
Korean j.of Pharm.2017, 70-76
Applied Biological Chemistry2023, 66:85.
JPC-Journal of Planar Chromatography2023, 36:179-190
Front Immunol.2020, 11:598556.
J Chromatogr Sci.2015, 53(5):824-9
Metabolites2022, 12(6),507.
Indian J Pharm Sci.2022, 84(4): 874-882.
Phytomedicine.2022, 110:154597.
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Australian Journal of Chemistry,1969, 22(6) 1271 - 1275
Tumour inhibitory plants. The alkaloids of Bruguiera sexangula and Bruguiera exaristata (Rhizophoraceae)[Reference:
WebLink]
METHODS AND RESULTS:
Tropine and tropine esters of acetic, propionic (a new natural ester), n-butyric (a new natural ester), isobutyric, α-methylbutyric or isovaleric, and benzoic acids have been identified in crude alkaloid mixtures from the bark of B. sexangula and B. exaristata.
CONCLUSIONS:
The major component of the mixtures from both species was a new alkaloid, Brugine, (+)-tropine 1,2-dithiolan-3-carboxylate.
