Apohyoscine
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Planta Medica, 1980,38(4):356-358.
Metabolism of hyoscine fed to the aerial parts of Solandra grandiflora.[Reference:
WebLink]
METHODS AND RESULTS:
(-)-Hyoscine infiltrated into the aerial parts of S. grandiflora was transformed to ( plus or minus )-hyoscine, Apohyoscine, ( plus or minus )-norhyoscine, scopine and oscine.
Phytochemistry,1976,15(2): 287-9.
Biosynthesis of C6-C3 acids in Datura innoxia[Reference:
WebLink]
METHODS AND RESULTS:
Datura innoxia plants were fed via the roots with cinnamic acid-[214C], (±)-phenyllactic (2-hydroxy-3-phenylpropanoic) acid-[214C] and phenylalanine-[2-14C]. In each case Apohyoscine, hyoscine, hyoscyamine and littorine were isolated from the aerial parts, and hyoscine, hyoscyamine and littorine from the roots. Cinnamic acid was not incorporated into the acid moieties of the alkaloids. Phenyllactic acid served as a better precursor than phenylalanine for tropic acid (hyoscine and hyoscyamine) and atropic acid (Apohyoscine).
CONCLUSIONS:
Phenylalanine served as an effective precursor for the phenyllactic acid moiety of Littorine.
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