Tessaric acid

Tessaric acid
Product Name Tessaric acid
CAS No.: 58142-10-2
Catalog No.: CFN95182
Molecular Formula: C15H20O3
Molecular Weight: 248.3 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The herbs of Tessaria absinthioides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/5mg
Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Evid Based Complement Alternat Med.2018, 2018:4259603
  • Biochem Biophys Res Commun.2017, 494(3-4):587-593
  • Evid Based Complement Alternat Med.2017, 2017:6360836
  • Process Biochemistry2019, 85:106-115
  • Molecules.2020, 25(3):734
  • Molecules.2018, 23(7):E1659
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • Int J Mol Sci.2018, 19(9):E2528
  • Analytical sci. & Tech2016, 186-193
  • Phytother Res.2019, 33(7):1784-1793
  • Aristolone

    Catalog No: CFN96139
    CAS No: 6831-17-0
    Price: $298/20mg
    Axinysone B

    Catalog No: CFN89436
    CAS No: 1114491-60-9
    Price: $398/5mg
    Kanshone H

    Catalog No: CFN89349
    CAS No: 1445952-33-9
    Price: Inquiry(manager@chemfaces.com)
    1(10)-Aristolen-2-one

    Catalog No: CFN89356
    CAS No: 28398-06-3
    Price: Inquiry(manager@chemfaces.com)
    Aristola-1(10),8-dien-2-one

    Catalog No: CFN89328
    CAS No: 22391-34-0
    Price: $318/5mg
    Debilon

    Catalog No: CFN89419
    CAS No: 26808-51-5
    Price: $398/5 mg
    Nardoaristolone B

    Catalog No: CFN95203
    CAS No: 1422517-82-5
    Price: $398/5mg
    Kanshone A

    Catalog No: CFN96977
    CAS No: 115356-18-8
    Price: $318/5mg
    Nardosinonediol

    Catalog No: CFN89546
    CAS No: 20489-11-6
    Price: Inquiry(manager@chemfaces.com)
    Isonardosinone

    Catalog No: CFN95180
    CAS No: 27062-01-7
    Price: $318/10mg
    Bioorg Med Chem. 2009 Sep 1;17(17):6251-6.
    Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines.[Pubmed: 19664930 ]

    METHODS AND RESULTS:
    A series of analogs were synthesized in a straightforward manner from naturally available sesquiterpenes ilicic acid and Tessaric acid. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, HBL-100, HeLa, SW1573, T-47D and WiDr. The most potent analog induced considerably growth inhibition in the range 1.9-4.5 microM.
    CONCLUSIONS:
    Cell cycle studies for Tessaric acid derivatives indicated a prominent arrest of the cell cycle at the G(2)/M phase. Damage to the cells was permanent as determine by the so called 24+24 drug schedule.
    Z Naturforsch C. 2005 Nov-Dec;60(11-12):855-61.
    Antifeedant/insecticidal terpenes from asteraceae and labiatae species native to Argentinean semi-arid lands.[Pubmed: 16402545 ]
    To validate the potential as added-value resources of Asteraceae and Labiatae species of Argentinean semi-arid lands, we have selected 13 of their major terpenoids belonging to several chemical classes and tested their insect antifeedant and toxic activity on the herbivorous insects Spodoptera littoralis and Leptinotarsa decemlineata.
    METHODS AND RESULTS:
    The antifeedant effects of the test compounds were structure- and species-dependent. The most active antifeedant to L. decemlineata was the eudesmane sesquiterpene gamma-costic acid (13), followed by the labdane diterpene 2alpha,3alpha-dihydroxycativic acid (8), the clerodane diterpenes 6-acetylteucjaponin B (5), bacchotricuneatin A (1), bartemidiolide (7), butanolide (4), and the sesquiterpenes ilicic acid (11) and Tessaric acid (10) (eudesmane and eremophilane type, respectively). S. littoralis was only affected by the clerodanes and showed the strongest response to salviarin (3) and 5, followed by hawtriwaic acid (6) and 12-epi-bacchotricuneatin A (2).
    CONCLUSIONS:
    Orally injected S. littoralis larvae were negatively affected by 5. Most of the diterpenes had selective cytotoxic effects to insect-derived Sf9 cells with the clerodane 1 being the most active, followed by the eudesmane costic acid (12), the only cytotoxic sesquiterpene. None of these compounds was cytotoxic to mammalian CHO cells.
    J Chem Ecol. 2003 Jan;29(1):175-87.
    Allelochemical effects of eudesmane and eremophilane sesquiterpenes on Tribolium castaneum larvae.[Pubmed: 12647861]

    METHODS AND RESULTS:
    Eight eudesmane and eremophilane sesquiterpenes administered to Tribolium castaneum larvae caused different allelochemical effects. Topical application of 3-oxo-gamma-costic acid produced the greatest lengthening in the duration of the pupal stage. Morphological deformities were found, specifically when ilicic, costic, and gamma-costic acids and costic aldehyde were used. Ilicic acid exhibited the major toxicity 72 hr following topical application. All compounds were significantly toxic at the end point of the experiment (60 days). Treated surface toxicity was lower than when topical assays were carried out.
    CONCLUSIONS:
    Responses to Tessaric acid in choice bioassays had the highest attractive effect. Maximum repellency was caused by the 3-oxo-gamma-costic acid. However, experimental series carried out using gamma-costic acid, eremophilan-1(10),2,11(13)-trien-12-oic acid, costic aldehyde, and ilicic aldehyde showed no clear response.
    Picrasidine I

    Catalog No: CFN99019
    CAS No: 100234-59-1
    Price: $368/5mg
    Nodakenin

    Catalog No: CFN90232
    CAS No: 495-31-8
    Price: $138/20mg
    Picrasidine Q

    Catalog No: CFN92205
    CAS No: 101219-61-8
    Price: $388/10mg
    Glychionide A

    Catalog No: CFN92280
    CAS No: 119152-50-0
    Price: $318/5mg
    6alpha-Hydroxypolyporenic acid C

    Catalog No: CFN92741
    CAS No: 24513-63-1
    Price: $533/5mg
    Secologanic acid

    Catalog No: CFN95028
    CAS No: 60077-46-5
    Price: $318/10mg
    Physalin G

    Catalog No: CFN95104
    CAS No: 76045-38-0
    Price: $388/5mg
    Tuberosin

    Catalog No: CFN95107
    CAS No: 41347-45-9
    Price: $218/5mg
    Polygalin J

    Catalog No: CFN95175
    CAS No: N/A
    Price: $318/5mg
    N-Methylcorydalmine

    Catalog No: CFN95204
    CAS No: 81010-29-9
    Price: $398/5mg