Neopetasitenine
Petasitenine and neopetasitenine show strong hepatotoxic activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Mol Biol Rep.2022, doi: 10.1007
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Horticulture Research2023, uhad164.
The Thai Journal of Pharmaceutical Sciences2023, 47(3):3.
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Journal of Medicinal Food2023, Vol.26(10).
Herbal Formula Science2024, 32(2):155-179.
J.the Korean Socie. Food Sci.&Nut.2023; 52(1):26-39.
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Biochemical Systematics and Ecology,2007,35(10): 676–681.
Pyrrolizidine alkaloids in the antipodean genus Brachyglottis (Asteraceae)[Reference:
WebLink]
METHODS AND RESULTS:
Perdicioides “Alfred Atkinson” horticultural hybrid; Brachyglottis sciadophila contained clivorine and Neopetasitenine (acetylfukinotoxin); the latter alkaloid was also present in B. kirkii together with the previously reported senkirkine and senkirkine 12-acetate.
Chemistry Letters, 1976 (5) :461-464.
Isolation and the structures of two new alkaloids, petasitenine and neopetasitenine, from Petasites japonicus Maxim[Reference:
WebLink]
METHODS AND RESULTS:
Two new pyrrolizidine alkaloids revealing strong hepatotoxic activity were isolated from Petasites japonicus Maxim., and their structures were deduced to be petasitenine (3) and Neopetasitenine (4), respectively based on chemical and spectral evidence.
