Neolitsine
Neolitsine has anthelmintic activity, it exhibits EC90 values (concentration at which 90% loss of larval motility is observed) of 6.4 microg/mL.Neolitsine and dicentrine have potent vasorelaxing effects on precontracted rat aortic preparations with mean IC 50 values between 0.08 and 2.48 microM.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Horticulture Research2023, uhad259
J Breast Cancer.2015, 18(2):112-118
Biomed Pharmacother.2020, 131:110673.
Food Science and Biotechnology2023, 2023:1007
J. Mater. Life Sci.2024, 3:2:78-87
J of L. Chroma.&Related Tech2017, 252-258
Plant Physiol Biochem.2019, 144:355-364
Food Chem.2018, 262:78-85
Nutrients.2018, 10(10)
Biomolecules.2020, 10(2):E184
Related and Featured Products
Planta Med. 2007 Mar;73(3):296-7.
Anthelmintic activity of aporphine alkaloids from Cissampelos capensis.[Pubmed:
17309014 ]
METHODS AND RESULTS:
Two known aporphine alkaloids, (S)-dicentrine (1) and (S)-Neolitsine (2), have been isolated from the MeOH extract of the aerial parts of Cissampelos capensis (Menispermaceae). The structures of these compounds were elucidated by NMR and MS analysis and comparison to literature data. These compounds were isolated by bioassay-guided fractionation using the Haemonchus contortus larval development assay.
CONCLUSIONS:
Compounds 1 and 2 exhibited EC90 values (concentration at which 90% loss of larval motility is observed) of 6.3 and 6.4 microg/mL, respectively. In an IN VIVO assay, administration of 1 resulted in 67% reduction of worm counts in mice at 25 mg/kg when dosed orally.
J Nat Prod. 2008 Feb;71(2):289-91.
Vasorelaxing alkaloids and flavonoids from Cassytha filiformis.[Pubmed:
18217715 ]
METHODS AND RESULTS:
Two new aporphine alkaloids, isofiliformine ( 1) and cassythic acid ( 3), along with 22 known compounds were isolated from whole herb of Cassytha filiformis. Cassythic acid ( 3), cassythine ( 4), Neolitsine ( 7), and dicentrine ( 8) had potent vasorelaxing effects on precontracted rat aortic preparations with mean IC 50 values between 0.08 and 2.48 microM. Compounds 1, 1,2-methylenedioxy-3,10,11-trimethoxyaporphine ( 2), (-)- O-methylflavinatine ( 10), (-)-salutaridine ( 11), isohamnetin-3- O-beta-glucoside, and isohamnetin-3- O-rutinoside exerted moderate vessel-relaxing activities with IC 50 values from 16.50 to 32.81 microM at the test concentrations.
