N-Benzyloctadecanamide

Phytochem Anal. 2005 Nov-Dec;16(6):463-9.

Analysis of macamides in samples of Maca (Lepidium meyenii) by HPLC-UV-MS/MS.[Pubmed: 16315492]

The macamides are a distinct class of secondary metabolites that have so far been found only in Lepidium meyenii Walp. (Maca).
METHODS AND RESULTS:
Using HPLC-UV-MS/MS, the main macamides have been identified as n-benzylhexadecanamide, n-benzyl-(9Z)-octadecenamide, n-benzyl-(9Z, 12Z)-octadecadienamide, n-benzyl-(9Z, 12Z, 15Z)-octadecatrienamide and N-Benzyloctadecanamide. The identities of n-benzyl-(9Z)-octadecenamide and n-benzyl-(9Z, 12Z)-octadecadienamide were confirmed by comparison of chromatographic and spectral properties with synthetic analogues. Total macamides have been quantified by HPLC-UV in plant material from different vendors using n-benzylhexadecanamide as an external standard.
CONCLUSIONS:
The amount of macamides in the dried plant material ranged from 0.0016 to 0.0123%.

Chinese Traditional & Herbal Drugs, 2014, 45(17):2457-2460.

Chemical constituents in Lepidium meyenii cultivated in Jilin.[Reference: WebLink]

To study the chemical constituents from the dried rhizome of Lepidium meyenii (Maca) cultivated in Jilin.
METHODS AND RESULTS:
The chemical constituents were isolated and purified with macroreticular resin, silica gel, ODS column chromatography, preparation HPLC, etc. The structures of the compounds were identified by physicochemical properties and various spectroscopic methods. Thirteen compounds were isolated as N-methyl-3-hydroxy-benzeneacetamide (1), N-Benzyloctadecanamide (2), benzeneacetamide (3), benzylamine (4), 3-methoxyphenylacetic acid (5), phenylacetic acid (6), 4-hydroxy-3-methoxybenzoic acid (7), nicotinic acid (8), 3, 4-dihydroxy-benzoic acid methyl ester (9), adenosine (10), L-valine (11), daueosterol (12), and β-sitosterol (13).
CONCLUSIONS:
Compound 1 is identifled as a new natural compound, and compounds 3-6 and 9-12 are obtained from L. meyenii for the first time.