Myricadiol
Myricadiol is a potential lead compound for synthetic anti-cancer drugs.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Environ Toxicol.2024, 39(4):2417-2428.
J Vet Sci.2020, 21(3):e39.
University of East Anglia2023, 93969.
Onco Targets Ther.2017, 10:3467-3474
Drug Chem Toxicol.2020, 1-14.
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Planta Med. 1996 Dec;62(6):519-22.
Myricadiol and other taraxerenes from Scaevola spinescens.[Pubmed:
17252493]
METHODS AND RESULTS:
Scaevola spinescens R. Br. (Goodeniaceae), a West Australian semi-arid native plant, has been found to contain a number of pentacyclic triterpenoid compounds of the taraxerene type in high yield compared with other species in which these compounds are known to occur. Isolation of these molecules, which are potential lead compounds for synthetic anti-cancer drugs, was achieved by partitioning the diethyl ether-soluble fraction, of the methanol Soxhlet extract, between hexane and aqueous methanol, followed by base extraction of minor components from the methanol isolate and recrystallisation or column chromatography.
CONCLUSIONS:
The major component isolated from the extract, and main subject of this report, is the pentacyclic triterpenoid, 14-taraxerene-3,28-diol (1; Myricadiol).
