Myrciaphenone A
Myrciaphenone A is a natural product from Limoniastrum feei (Girard) Batt.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Z Naturforsch C. 2008 Nov-Dec;63(11-12):801-7.
Activity-guided isolation of antioxidant principles from Limoniastrum feei (Girard) Batt.[Pubmed:
19227826]
METHODS AND RESULTS:
Bioguided fractionation of a leaves extract from Limoniastrum feei (Girard) Batt. (Plumbaginaceae) led to the isolation of seven polyphenolic constituents: gallic acid (1), Myrciaphenone A (2), myricetin-3-O-beta-galactopyranoside (3-1), epigallocatechin gallate (3-2), myricetin 3-O-alpha-rhamnopyranoside (4), quercetin (5) and myricetin (6).
CONCLUSIONS:
Gallic acid was the most antioxidant compound in DPPH [(0.94 +/- 0.68) microg/mL] and FRAP [(0.83 +/- 0.15) microM Fe2+/mL] tests, whereas myricetin was a more specific superoxide radical scavenger since it was the most active product in the superoxide nitroblue tetrazolium hypoxanthine/xanthine oxidase test [(1.86 +/- 0.12) microg/mL].
Chem Pharm Bull (Tokyo). 1998 Jan;46(1):113-9.
Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): structures of myrciacitrins I and II and myrciaphenones A and B[Pubmed:
9468642]
METHODS AND RESULTS:
The methanolic extract and ethyl acetate-soluble portion from a Brazilian natural medicine, the leaves of Myrcia multiflora DC., which has been used as a specific medicine against diabetes, were found to show inhibitory activities on aldose reductase and alpha-glucosidase and on the increase of serum glucose level in sucrose-loaded rats and in alloxan-induced diabetic mice. From the ethyl acetate-soluble portion, new flavanone glucosides, myrciacitrins I and II, and new acetophenone glucosides, Myrciaphenone A and myrciaphenone B, were isolated together with several known compounds such as five flavonol glycosides, myricitrin, mearnsitrin, quercitrin, desmanthin-1, and guaijaverin.
CONCLUSIONS:
The structures of new compounds were determined on the basis of physicochemical and chemical evidence. The principal components of this natural medicine including new glucosides, myrciacitrin I and myrciaphenone B, were found to show potent inhibitory activities on aldose reductase and alpha-glucosidase.
