Lusianthridin
Lusianthridin shows appreciable cytotoxicity against human lung cancer cell lines. It exhibits anti-migratory property at nontoxic concentrations.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Molecules.2021, 26(2):313.
Int J Mol Sci.2023, 24(18):13713.
Res Pharm Sci.2023, 18(3):244-261.
Front Microbiol.2023, 14:921653.
Nutrients.2024, 16(20):3521.
PLoS One.2017, 12(3):e0173585
Food Chem.2024, 458:140201.
bioRxiv - Biochemistry2023, 548213.
Enzyme Microb Technol.2022, 161:110111.
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Evid Based Complement Alternat Med. 2015;2015:350410.
Cytotoxic and Antimigratory Activities of Phenolic Compounds from Dendrobium brymerianum.[Pubmed:
25685168]
METHODS AND RESULTS:
Chromatographic separation of a methanol extract prepared from the whole plant of Dendrobium brymerianum led to the isolation of eight phenolic compounds. Among the isolated compounds (1-8), moscatilin (1), gigantol (3), Lusianthridin (4), and dendroflorin (6) showed appreciable cytotoxicity against human lung cancer cell lines with IC50 values of 196.7, 23.4, 65.0, and 125.8 μg/mL, respectively, and exhibited antimigratory property at nontoxic concentrations.
CONCLUSIONS:
This study is the first report on the biological activities of this plant.
