Linderaspirone A

Linderaspirone A
Product Name Linderaspirone A
CAS No.: 1235126-46-1
Catalog No.: CFN99350
Molecular Formula: C34H32O10
Molecular Weight: 600.6 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Yellow powder
Source: The roots of Lindera aggregata( Sims) Kosterm
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Linderaspirone A shows significant activity against glucosamine-inducedinsulin resistance.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Bioorg Med Chem.2020, 28(12):115553.
  • Food Sci Nutr.2019, 8(1):246-256
  • Cells.2021, 10(11):2919.
  • Planta Med.2023, a-2192-2281.
  • J Biomed Sci.2020, 27(1):60.
  • Vietnam Journal of Food Control2022, 5(3):pp.390-401.
  • Academic J of Second Military Medical University2018, 39(11)
  • J. of Med. Plant Research.2013, 90-151
  • Chemistry of Natural Compounds2020, 56,423-426
  • Acta Biochim Pol.2015, 62(2):253-8
  • Genkwanin

    Catalog No: CFN98670
    CAS No: 437-64-9
    Price: $60/20mg
    Paclitaxel

    Catalog No: CFN97759
    CAS No: 33069-62-4
    Price: $30/20mg
    Apigenin 5-O-beta-D-glucopyranoside

    Catalog No: CFN98352
    CAS No: 28757-27-9
    Price: $318/10mg
    Puerarin

    Catalog No: CFN99169
    CAS No: 3681-99-0
    Price: $30/20mg
    Dauricine

    Catalog No: CFN98129
    CAS No: 524-17-4
    Price: $98/20mg
    Org Lett. 2011 May 6;13(9):2192-5.
    Biomimetic total syntheses of linderaspirone A and bi-linderone and revisions of their biosynthetic pathways.[Pubmed: 21446662]

    METHODS AND RESULTS:
    Simple exposure to sunlight is sufficient for triggering photochemical [2 + 2] cycloaddition-Cope or radical rearrangement cascades in the naturally occurring methyl linderone, leading to efficient biomimetic total syntheses of Linderaspirone A and bi-linderone, two recently discovered bioactive spirocyclopentenedione natural products.
    Org Lett. 2010 Jul 16;12(14):3196-9.
    A pair of windmill-shaped enantiomers from Lindera aggregata with activity toward improvement of insulin sensitivity.[Pubmed: 20545338]

    METHODS AND RESULTS:
    (+)-Linderaspirone A and (-)-Linderaspirone A, a pair of natural windmill-shaped enantiomers, were isolated from the traditional Chinese medicine plant Lindera aggregate by HPLC using a chiral column, achieving over 98% ee. Their structures and absolute configurations were determined on the basis of extensive analysis of NMR spectra, crystal X-ray diffraction, and calculation of the optical rotations (OR).
    CONCLUSIONS:
    They have an unprecedented carbon skeleton and showed significant activity against glucosamine-induced insulin resistance.
    6''-O-acetylsaikosaponin A

    Catalog No: CFN95086
    CAS No: 64340-46-1
    Price: $268/10mg
    Microgrewiapine A

    Catalog No: CFN95125
    CAS No: 1420777-30-5
    Price: $413/5mg
    Tessaric acid

    Catalog No: CFN95182
    CAS No: 58142-10-2
    Price: $318/5mg
    N1,N5,N10-(E)-tri-p-coumaroylspermidine

    Catalog No: CFN95256
    CAS No: 364368-18-3
    Price: $388/10mg
    N-trans-p-Coumaroyltyrosine

    Catalog No: CFN95279
    CAS No: 77201-66-2
    Price: $318/10mg
    4'-O-Methyllucenin II (Diosmetin 6,8-di-C-glucoside)

    Catalog No: CFN95344
    CAS No: 98813-28-6
    Price: $318/10mg
    Japondipsaponin E1

    Catalog No: CFN95354
    CAS No: 175586-66-0
    Price: $318/5mg
    Isosilychristin

    Catalog No: CFN95369
    CAS No: 77182-66-2
    Price: $318/5mg
    Isochlorogenic acid C 4'-O-glucoside

    Catalog No: CFN95405
    CAS No: N/A
    Price: $413/5mg
    threo-Guaiacylglycerol-beta-coniferyl aldehyde ether

    Catalog No: CFN95417
    CAS No: 650600-33-2
    Price: $318/5mg