Kolavenol

Kolavenol
Product Name Kolavenol
CAS No.: 19941-83-4
Catalog No.: CFN97792
Molecular Formula: C20H34O
Molecular Weight: 290.49 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Targets: Antifection
Source: The herbs of Eupatorium adenophora
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Kolavenol shows a trypanocidal activity with an IC50 value of 2.5 microg/ml (8.6 microM) against Trypanosoma brucei rhodesiense, the causing agent of the acute form of human African trypanosomiasis.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Front Pharmacol.2021, 12:765521.
  • Int J Mol Sci.2021, 22(16):8604.
  • Front Pharmacol.2022, 13:870553.
  • Life Sci.2023, 332:122107.
  • Pharmacol Rep.2017, 69(6):1224-1231
  • Journal of Ginseng Research2021, 3 June.
  • J Appl Pharm Sci.2022, 12(04):044-053
  • Processes2021, 9(1), 153;
  • Natural Product Communications2021, 16(9):1-10.
  • Food Funct.2022, doi: 10.1039
  • Monomethyl kolavate

    Catalog No: CFN98262
    CAS No: 24513-41-5
    Price: Inquiry(manager@chemfaces.com)
    Scutebata E

    Catalog No: CFN99325
    CAS No: 1207181-61-0
    Price: Inquiry(manager@chemfaces.com)
    Scutebata F

    Catalog No: CFN99326
    CAS No: 1207181-62-1
    Price: Inquiry(manager@chemfaces.com)
    Scutebata G

    Catalog No: CFN99327
    CAS No: 1207181-63-2
    Price: Inquiry(manager@chemfaces.com)
    6-O-Nicotinoylscutebarbatine G

    Catalog No: CFN96994
    CAS No: 1206805-30-2
    Price: Inquiry(manager@chemfaces.com)
    Scutebarbatine W

    Catalog No: CFN96705
    CAS No: 1312716-25-8
    Price: Inquiry(manager@chemfaces.com)
    2-Oxokolavelool

    Catalog No: CFN97783
    CAS No: 221466-41-7
    Price: Inquiry(manager@chemfaces.com)
    Kolavenol

    Catalog No: CFN97792
    CAS No: 19941-83-4
    Price: Inquiry(manager@chemfaces.com)
    2-Oxokolavenol

    Catalog No: CFN97832
    CAS No: 130395-82-3
    Price: Inquiry(manager@chemfaces.com)
    16-Oxocleroda-3,13E-dien-15-oic acid

    Catalog No: CFN96984
    CAS No: 117620-72-1
    Price: Inquiry(manager@chemfaces.com)
    J Ethnopharmacol. 1998 Jul;61(3):179-83.
    Bioassay-guided isolation of a diastereoisomer of kolavenol from Entada abyssinica active on Trypanosoma brucei rhodesiense.[Pubmed: 9705008 ]

    METHODS AND RESULTS:
    Bioassay-guided fractionation of the dichloromethane rootbark extract of Entada abyssinica (Leguminosae), a plant used by traditional healers in Uganda for the treatment of sleeping sickness, led to the isolation of a diastereoisomer of the clerodane type diterpene Kolavenol.
    CONCLUSIONS:
    This is the first report on this compound. It showed a trypanocidal activity with an IC50 value of 2.5 microg/ml (8.6 microM) against Trypanosoma brucei rhodesiense, the causing agent of the acute form of human African trypanosomiasis.
    Lappaol C

    Catalog No: CFN95068
    CAS No: 64855-00-1
    Price: $333/10mg
    Stevioside D

    Catalog No: CFN95230
    CAS No: 1310055-59-4
    Price: $463/5mg
    New compound 5

    Catalog No: CFN95258
    CAS No: N/A
    Price: $413/5mg
    Eriodictyol 7-O-glucuronide

    Catalog No: CFN95290
    CAS No: 125535-06-0
    Price: $318/10mg
    Isomargaritene

    Catalog No: CFN95304
    CAS No: 64271-11-0
    Price: $318/10mg
    Japondipsaponin E1

    Catalog No: CFN95354
    CAS No: 175586-66-0
    Price: $318/5mg
    Violanone

    Catalog No: CFN95385
    CAS No: 52250-38-1
    Price: $318/10mg
    Otobaphenol

    Catalog No: CFN95476
    CAS No: 10240-16-1
    Price: $318/10mg
    Bayin

    Catalog No: CFN95539
    CAS No: 3681-96-7
    Price: $318/5mg
    Mahuannin G

    Catalog No: CFN95553
    CAS No: N/A
    Price: $318/5mg