Kansuiphorin C
Kansuiphorin C shows cytotoxic activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Biomed Pharmacother.2019, 116:108987
Plos One.2020, 10.1371
Arch Toxicol.2024, 98(5):1415-1436.
UDC.2020, 19(4).
ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
European Journal of Integrative Medicine2018, 20:165-172
Journal of Functional Foods2023, 104:105542
Neurotox Res.2020, 38(1):163-174.
Bioorg Chem.2024, 145:107182.
Plant Physiol Biochem.2023, 203:108073.
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Int J Mol Sci. 2012;13(9):11247-59.
Bio-guided isolation of the cytotoxic terpenoids from the roots of Euphorbia kansui against human normal cell lines L-O2 and GES-1.[Pubmed:
23109850]
METHODS AND RESULTS:
Bioassay-guided separation of the 95% ethanol extract from the roots of E. kansui led to the isolation of 12 diverse terpenoids whose structures were identified by (1)H, (13)C NMR spectroscopy and ESI-MS as kansuinine A (1), kansuinine B (2), kansuinine C (3), Kansuiphorin C (4), 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol (5), 3-O-(2'E,4'Edecadienoyl)-20-O-acetylingenol (6), 3-O-(2'E,4'Z-decadienoyl)-20-deoxyingenol (7), 3-O-benzoyl-20-deoxyingenol (8), 5-O-benzoyl-20-deoxyingenol (9), kansenone (10), epi-kansenone (11), euphol (12).
CONCLUSIONS:
All these 12 terpernoids were evaluated in vitro for cytotoxicity on L-O2 and GES-1 cell lines.
