Isotachioside

Isotachioside
Product Name Isotachioside
CAS No.: 31427-08-4
Catalog No.: CFN98398
Molecular Formula: C13H18O8
Molecular Weight: 302.3 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Targets: LOX
Source: The herbs of Vitex negundo Linn. var. cannabifolia
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price:
Isotachioside has15-lipoxygenase (15-LO) inhibitory activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • Isotachioside

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    Fitoterapia. 2006 Jun;77(4):290-5.
    Antioxidant and 15-lipoxygenase inhibitory activity of rotenoids, isoflavones and phenolic glycosides from Sarcolobus globosus.[Pubmed: 16701962]

    METHODS AND RESULTS:
    From Sarcolobus globosus, two rotenoids (villosinol and 6-oxo-6a,12a-dehydrodeguelin), one isoflavone (genistin) and four phenolic glycosides (vanillic acid 4-O-beta-d-glucoside, glucosyringic acid, tachioside and Isotachioside) were identified for the first time from this species. Extracts and compounds from S. globosus were evaluated for their DPPH radical scavenging and 15-lipoxygenase (15-LO) inhibitory activities.
    CONCLUSIONS:
    All tested rotenoids were found to inhibit 15-LO, while they lacked DPPH radical scavenging effect.
    Nat Prod Commun. 2013 Feb;8(2):181-2.
    Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities.[Pubmed: 23513723]

    METHODS AND RESULTS:
    Eight phenolic glycosides, tachioside (1), Isotachioside (2), koaburaside (3), 2,6-dimethoxy-4-hydroxyphenyl-1-O-beta-D-glucopyranoside (4), 4,6-dihydroxy-2-methoxyphenyl-1-O-beta-D-glucopyranoside (5), a mixture of erigeside C (6a) and salidroside (6b), and 6-hydroxyphenyl)-1-O-beta-D-glucopyranoside (7) were isolated from the stems of Lindera obtusiloba Blume.
    Zhongguo Zhong Yao Za Zhi. 2010 Nov;35(22):3007-9.
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    In order to study the chemical constituents of the plant of Hydrangea paniculata and provide reference for the study of the bioactive substances, we isolated nine compounds from the dried branches of H. paniculata.
    METHODS AND RESULTS:
    Their structures were determined by application of spectroscopic (NMR, MS) and chemical methods. These compounds were identified as skimmin (1), Isotachioside (2), 8-methoxy-7-O-beta-D-glucopyranosyloxy coumarin glycoside (3), scopolin (4), 1-(alpha-L-rhamnosyl-(1 --> 6) -O-beta-D-glucopyranosyloxy) - 3, 4, 5-trimethoxybenzene (5), apiosylskimmin (6), umbelliferone (7), scopoletin (8), 7-hydroxy-8-methoxycoumarin (9).
    CONCLUSIONS:
    Compounds 1 - 7 were isolated from H. paniculata for the first time.
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