Isosaxalin

Isosaxalin
Product Name Isosaxalin
CAS No.: 55481-86-2
Catalog No.: CFN98929
Molecular Formula: C16H15ClO5
Molecular Weight: 322.7 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The roots of Angelica polymorpha Maxim.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Isosaxalin, heraclenin and heraclenol 3'-Me ether have melanin biosynthesis inhibitory activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    METHODS AND RESULTS:
    During the screening for inhibitors of melanin biosynthesis from plant extract, Angelica polymorpha MAXIM which showed a high lecel of inhibition was selected. The inhibiting substances were purified form methanol extract of Angelica Polymorpha MAXIM followed by silica gel column chromatography and HPLC. The inhibitors were identified as heraclenin, Isosaxalin and heraclenol 3'-Me ether , by spectroscopic methods of ESI-MS, ©öH-NMR,©ö©øC-NMR, DEPT, HMQC and HMBC.
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