Ipatasertib (GDC-0068)

Ipatasertib (GDC-0068)
Product Name Ipatasertib (GDC-0068)
CAS No.: 1001264-89-6
Catalog No.: CFN60068
Molecular Formula: C24H32ClN5O2
Molecular Weight: 458.0 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Targets: Akt1/2/3 | PKA
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Ipatasertib (GDC-0068) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • Food Sci Biotechnol.2023, 32(9):1215-1223.
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  • Cell Mol Biol (Noisy-le-grand).2023, 69(15):167-173.
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  • Biomed Pharmacother.2024, 175:116770.
  • Front Pharmacol.2022, 13:883475.
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