Grosvenorin

Grosvenorin
Product Name Grosvenorin
CAS No.: 156980-60-8
Catalog No.: CFN99772
Molecular Formula: C33H40O19
Molecular Weight: 740.7 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Targets: Antifection
Source: The fruits of Siraitia grosuenorii
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $188/10mg
Grosvenorine exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Appl Microbiol.2022, 132(2):949-963.
  • Int J Mol Sci.2024, 25(5):2799.
  • Dermatologica Sinica2024, 42(1):p19-30.
  • Cancer Manag Res.2019, 11:483-500
  • PLoS One.2018, 13(3):e0193386
  • Cytotechnology2022, s10616
  • J Complement Integr Med.2024, jcim-2023-0177.
  • J Nat Prod.2017, 80(4):854-863
  • Int J Mol Sci.2022, 23(23):15213.
  • Molecules.2021, 26(12):3652.
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    Chem Biodivers. 2015 Nov;12(11):1652-64.
    The Gastrointestinal Tract Metabolism and Pharmacological Activities of Grosvenorine, a Major and Characteristic Flavonoid in the Fruits of Siraitia grosvenorii.[Pubmed: 26567944 ]
    Grosvenorine is the major flavonoid compound of the fruits of Siraitia grosvenorii (Swingle) C. Jeffrey, a medical plant endemic to China.
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    CONCLUSIONS:
    This study revealed that intestinal bacteria play an important role in the gastrointestinal metabolism of Grosvenorine and significantly affect its pharmacological activities.
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