Eupalitin

Eupalitin
Product Name Eupalitin
CAS No.: 29536-41-2
Catalog No.: CFN70334
Molecular Formula: C17H14O7
Molecular Weight: 330.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Targets: Caspase | ROS | Apoptosis
Source: The herbs of Artemisia asiatica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/10mg
Eupalitin has anti-cancer activity, it induces apoptosis in prostate carcinoma cells through ROS generation and increase of caspase-3 activity.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Pharmaceut Biomed2020, 182:113110
  • University of Stuttgart2021, 11682.
  • Acta Physiologiae Plantarum2015, 37:1736
  • Sci Rep.2025, 15(1):29590.
  • Molecules.2023, 28(7):3039.
  • Journal of Mushroom2023, 21(4):215-221.
  • Dicle Tip Dergisi2020, 47(2),423-430.
  • Chem Biodivers.2023, 20(10):e202300741.
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • J of the Society of Cosmetic Scientists of Korea2018, 44(4):407-417
  • 8-Methoxykaempferol

    Catalog No: CFN92382
    CAS No: 571-74-4
    Price: Inquiry(manager@chemfaces.com)
    Prudomestin

    Catalog No: CFN98453
    CAS No: 3443-28-5
    Price: $268/20mg
    5,7-Dihydroxy-3,4',8-trimethoxyflavone

    Catalog No: CFN99666
    CAS No: 1570-09-8
    Price: Inquiry(manager@chemfaces.com)
    5,7-Diacetoxy-3,4',8-trimethoxyflavone

    Catalog No: CFN98818
    CAS No: 5128-43-8
    Price: Inquiry(manager@chemfaces.com)
    4',5,7-Trihydroxy 3,6,8-trimethoxyflavone

    Catalog No: CFN70413
    CAS No: 57393-71-2
    Price: Inquiry(manager@chemfaces.com)
    Calycopterin

    Catalog No: CFN70374
    CAS No: 481-52-7
    Price: Inquiry(manager@chemfaces.com)
    Araneosol

    Catalog No: CFN98797
    CAS No: 50461-86-4
    Price: Inquiry(manager@chemfaces.com)
    2',3,5,7-Tetrahydroxyflavone

    Catalog No: CFN70373
    CAS No: 480-15-9
    Price: Inquiry(manager@chemfaces.com)
    Kaempferol

    Catalog No: CFN98838
    CAS No: 520-18-3
    Price: $30/20mg
    Kaempferol 3,4,7-triacetate

    Catalog No: CFN99479
    CAS No: 143724-69-0
    Price: Inquiry(manager@chemfaces.com)
    Cell Biology International, 2016, 40(2):196-203.
    Eupalitin induces apoptosis in prostate carcinoma cells through ROS generation and increase of caspase-3 activity.[Reference: WebLink]
    Prostate cancer is the second most common malignancy in the human reproductive system. Eupalitin is one of the O-methylated flavonol-exhibited enhanced cancer chemopreventive agents. The current study highlights the structural determination of Eupalitin and aims to explore the antitumor activity of Eupalitin in human prostate cancer cell (PC3) and its underlying mechanism.
    METHODS AND RESULTS:
    Eupalitin structure was determined by using FTIR, (1)H NMR, and (13)C NMR. PC3 cells were treated with increasing concentrations of Eupalitin, followed by analysis of the cell viability with an MTT assay. The results demonstrated that Eupalitin markedly inhibited the proliferation of PC3 cells in a concentration-dependent manner. The results from fluorescent microscopic analysis of nuclear condensation and intracellular ROS generation determined that Eupalitin significantly induced ROS level lead to nuclear apoptosis. Cell cycle analysis revealed that Eupalitin-induced cell cycle progression as a percentage of cells in G0/G1 phase decreased whereas S phase increased. Caspase-3 immunofluorescence analysis confirms the efficacy of Eupalitin-inducing apoptotic pathway and cell death.
    CONCLUSIONS:
    Thus, our study is helpful in understanding the mechanism underlying these effects in prostate cancer and it may provide novel molecular targets for prostate cancer therapy.
    Journal of Medicinal Plants Research,2013,7(20):1401-1405.
    Eupalitin from Asparagus falcatus (Linn.) has anti-cancer activity and induces activation of caspases 3/7 in human colorectal tumor cells.[Reference: WebLink]

    METHODS AND RESULTS:
    3,5,4′-Trihydroxy-6,7-dimethoxy-flavone (Eupalitin) has been isolated from the leaves ofAsparagus falcatus (Linn.). Anti-proliferation and apoptosis studies were conducted on Eupalitin. Results showed that Eupalitin exhibited significant cytotoxicity against human colorectal tumor cells. It is found that Eupalitin induces the activation of caspases 3/7, a hallmark of apoptosis.
    CONCLUSIONS:
    The study suggests that the anti-proliferative property of Eupalitin towards the human colorectal tumor cells may be probably due to its capability to induce apoptosis in cells.
    Ampelopsin G

    Catalog No: CFN95148
    CAS No: 151487-09-1
    Price: $318/5mg
    Stevia impurity (13-[(2-O-6-deoxy-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid beta-D-glucopyranosyl ester)

    Catalog No: CFN95229
    CAS No: 1309929-72-3
    Price: $463/5mg
    Lathyranoic acid A

    Catalog No: CFN95325
    CAS No: 850560-44-0
    Price: $318/5mg
    Hydroxytyrosol 1-O-glucoside

    Catalog No: CFN95367
    CAS No: 76873-99-9
    Price: $318/10mg
    New compound 13

    Catalog No: CFN95374
    CAS No: N/A
    Price: $318/5mg
    Moreollic acid

    Catalog No: CFN95437
    CAS No: 173792-68-2
    Price: $318/5mg
    Isosecotanapartholide

    Catalog No: CFN95471
    CAS No: 102926-01-2
    Price: $318/10mg
    Ganoderic acid Df

    Catalog No: CFN95514
    CAS No: 1352033-73-8
    Price: $318/5mg
    Apigenin-8-C-beta-D-glucopyranosyl-6-C-[alpha-L-rhamnopyranosyl-(1->2)]-beta-glucopyranoside

    Catalog No: CFN95548
    CAS No: N/A
    Price: $368/5mg
    Methyl ganoderenate D

    Catalog No: CFN95572
    CAS No: 748136-03-0
    Price: $413/5mg