Apocynol A
Apocynol A is a natural product from Hydrangea macrophylla.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Molecules.2020, 25(7):1625.
Biol Pharm Bull.2023, 46(2):245-256.
Int J Mol Sci.2022, 23(11):6104.
Metab Eng.2022, 75:143-152.
Pharm Biomed Res2023, 9(3):173-182.
J Ethnopharmacol.2023, 317:116789.
Tumour Biol.2015, 36(9):7027-34
Antioxidants (Basel).2020, 9(2): E119
Institute of Food Science & Technology2021, 18 December.
Molecules.2018, 23(11):E2837
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Zhongguo Zhong Yao Za Zhi. 2015 Feb;40(4):686-90.
Studies on chemical constituents of Zhuang medicine Excoecaria venenata and their cytotoxic activity.[Pubmed:
26137691]
METHODS AND RESULTS:
Fourteen compounds were isolated from 95% ethanol extract by silica gel, MCI, and ODS column chromatography. These compounds were respectively identified as quercetin (1), kaempferol (2), (+)-catechin (3), fraxin (4), protocatechuic acid (5), gallic acid (6), methyl gallate (7), ethyl gallate (8), Apocynol A (9), baccatin (10), cerevisterol (11), ellagic acid (12), 3, 3',4'-tri-0-methylellagic acid(13) and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate(14) by analyzing their spectral data and comparing with the previously reported literatures. Except for gallic acid (6), all other compounds were isolated from this plant for the first time.
CONCLUSIONS:
Compounds 1, 2 and 6 showed moderate anti-proliferation activities on tumor cells.