Deoxyflindissone
Deoxyflindissone exhibits significant cytotoxic activity against the A549, SK-OV-3, SK-MEL-2, and XF498 cell lines.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Nutrients.2018, 10(10)
Front Nutr.2023, 10:1168095.
J Agric Food Chem.2021, 69(11):3496-3510.
ACS Nano.2018, 12(4):3385-3396
Huazhong Agricultural University2022, pp34.
Phytomedicine.2019, 61:152813
Pharmaceutics.2022, 14(12):2765.
Nutrients.2023, 15(4):954.
Processes2021, 9(1), 153;
Korea Institute of Oriental Medicine2020, doi: 10.21203.
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J Nat Prod. 2011 Jan 28;74(1):54-9.
Tirucallane triterpenoids from Cornus walteri.[Pubmed:
21182258 ]
METHODS AND RESULTS:
Twelve new tirucallane triterpenoids, named cornusalterins A-L (1-12), and two known tirucallane triterpenoids, Deoxyflindissone (13) and (-)-leucophyllone (14), were isolated from a MeOH extract of stems and stem bark of Cornus walteri. The structures of the new compounds were determined by spectroscopic methods, including 1D and 2D NMR analyses.
CONCLUSIONS:
Compounds 12 and 13, possessing a tetrahydrofuran ring in the side chain, exhibited significant cytotoxic activity against the A549, SK-OV-3, SK-MEL-2, and XF498 cell lines.
