Denudatine
Denudatine has effects on action potential of ventricular fibers and has inhibition on arrhythmogenic action of aconitine.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Nat Prod. 1997 May;60(5):472-4.
Antifungal diterpenoid alkaloids from Delphinium denudatum.[Pubmed:
9170290]
METHODS AND RESULTS:
The roots of Delphinium denudatum have yielded a new diterpenoid alkaloid, 8-acetylheterophyllisine (1), in addition to the known alkaloids vilmorrianone (2), panicutine (3), Denudatine (4), isotalatizidine (5), and condelphine (6), as well as 3-hydroxy-2-methyl-4H-pyran-4-one (7). Compounds 1, 3, and 7 have not been isolated from this plant previously. The structures of compounds 1, 3, and 7 were determined through spectral and X-ray diffraction analyses.
CONCLUSIONS:
Compounds 1-3 have shown antifungal activity against a number of human pathogenic fungi.
Zhongguo Yao Li Xue Bao. 1982 Mar;3(1):32-4.
Effects of denudatine on action potential of ventricular fibers and its inhibition on arrhythmogenic action of aconitine.[Pubmed:
6211900]
METHODS AND RESULTS:
Effects of Denudatine on action potential of ventricular fibers and its inhibition on arrhythmogenic action of aconitine (author's transl)].